Achievements 2006 - 2007

Grants, Fellowships, and Awards

Coleman, John Robert (2006). Graduate Student Research Fellowship. The American Foundation for Aging Research, Raleigh, NC.

Lawrence, Paul (2006). Molecular Genetics and Microbiology Graduate Student Distinguished Service Award. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY.

Lucs, Alexandra (2006). Department of Molecular Genetics and Microbiology 2006 Retreat Outstanding Poster Award. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY.

Medina, Gisselle (2006). Irving Abrahams Award for Outstanding Achievement by a Graduate Student. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY.

Noel, Betty (2006). Teresa Haire Memorial Award. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY.

Runco, Lisa (2006). ASM Travel Grant Award. American Society for Microbiology, Washington, D.C.

Ullman, Amanda (2006). Molecular Genetics and Microbiology Graduate Student Distinguished Service Award. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY.


Jointly Authored Publications/Research Reports/Reviews

Aranda, V., Haire, T., Nolan, M.E., Calarco, J.P., Rosenberg, A.Z., Fawcett, J.P., Pawson, T., and Muthuswamy, S. (2006) Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nature Cell Biology (8): 1235-1245.

Ballon, D.R., Flanary, P.L., Gladue, D.P., Konopka, J.B., Dohlman, H.G., and Thorner J.W. (2006) DEP domains link a regulator-of-G-protein-signaling protein to its cognate G-protein-coupled receptor. Cell (126): 1079-93.

Coleman, J.R. (2007) The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages. Virology Journal (4): 9.

Goldstein, R.S., Gallowitsch-Puerta, M., Yang, L., Rosas-Ballina, M., Huston, J.M., Czura, C.J., Lee, D.C., Ward, M.E., Bruchfield, A.N., Wang, H., Lesser, M.L., Church, A.L., Litroff, A.H., Sama, A.E., and Tracey, K.J. (2006) Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock (25): 571-574.

Hicks, J., Krasnitz, A., Lakshmi, B., Navin, N., Riggs, M., Leibu, E., Esposito, D., Alexander, J., Troge, J., Grubor, V., Yoon, S., Wigler, M., Ye, K., Borresen-Dale, A.L., Naume, B., Schlicting, E., Norton, L., Hagerstrom, T., Skoog, L., Auer, G., Maner, S., Lundin, P., and Zetterberg, A. (2006) Novel patterns of genome rearrangements and their association with survival in breast cancer. Genome Research (16): 1465-1479.

Huston, J.M., Ochani, M., Rosas-Ballina, M., Liao, H., Ochani, K., Pavlov, V.A., Gallowitsch-Puerta, M., Ashok, M., Czura, C.J., Foxwell, B., Tracey, K.J., and Ulloa, L. (2006) Splenectomy inactivates the cholinergic anti-inflammatory pathway during lethal endotoxemia and polymicrobial sepsis. Journal of Experimental Medicine (203): 1623-1628.

Kruh, N.A., Rawat, R., and Tonge, P.J. Probing mechanisms of resistance to the tuberculosis drug isoniazid: conformational changes caused by inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis. Protein Science (16): 1617-1627.

Lee, H., Liu, Y., Mejia, E., Paul, A.V., and Wimmer, E. (2006) The C-terminal hydrophobic domain of hepatitis C virus RNA polymerase NS5B can be replaced with a heterologous domain of poliovirus protein 3A. Journal of Virology (80): 11343-11354.

Mueller, S., Papamichail, D., Coleman, J.R., Skiena, S., and Wimmer, E. (2006) Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. Journal of Virology (80): 9687-9696.

Navin, N., Grubor, V., Hicks, J., Leibu, E., Thomas, E., Troge, J., Riggs, M., Lundin, P., Maner, S., Sebat, J., Zetterberg, A., and Wigler, M. (2006) PROBER: Oligonucleotide FISH probe design software. Bioinformatics (22): 2437-2438.

Pelham, R.J., Rodgers, L., Hall, I., Lucito, R., Nguyen, K.C., Navin, N., Hicks, J., Mu, D., Powers, S., Wigler, M., and Botstein, D. (2006) Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proceedings of the National Academy of Sciences USA (103): 19848-19853.

Qin, S., Wang, H., Yuan, R., Li, H., Ochani, M., Ochani, K., Rosas-Ballina, M., Czura, C.J., Huston, J.M., Miller, E., Lin, X., Sherry, B., Kumar, A., Larosa, G., Newman, W., Tracey, K.J., and Yang, H. (2006) Role of HMBG1 in apoptosis-mediated sepsis lethality. Journal of Experimental Medicine (203): 1637-1642.

Ullman, A.J., Reich, N.C., and Hearing, P. (2007) The adenovirus E4 ORF3 protein inhibits the interferon-mediated antiviral response. Journal of Virology (81): 4744-4752.

Yu, M., Wang, H., Ding, A., Golenbock, D.T., Latz, E., Czura C.J., Fenton, M.J., Tracey, K.J., and Yang, H. (2006) HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock (26): 174-179.


Conferences/Colloquiums, Presentations, Symposiums, Workshops

Kruh, N., Bargaro, J., Xu, H., and Tonge, P. (2007) A Novel Interaction Between the FAS-II and PDIM Biosynthetic Pathways. Keystone Symposium on Tuberculosis: From Lab Research to Field Trials. Vancouver, British Columbia.

Lilo, S., and Bliska, J.B. (2007) Type III Secretion System-Dependent Caspase-1 Activation and IL-1β Secretion in Macrophages Infected with Yersinia pestis. American Society for Microbiology 107th General Meeting. Toronto, Ontario.

Lucs, A., and Muthuswamy, S. (2006) Structure Function Analysis of ErbB2’s Ability to Disrupt 3D Acini. Mechanisms and Models of Cancer. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

Lucs, A., and Muthuswamy, S. (2007) Y1226/7 and Y1253 Mediate ErbB2 Induced Protection From Apoptosis. Phosphorylation, Signaling & Disease. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

Mueller, S., Papamichail, D., Coleman, J.R., Skiena, S., and Wimmer, E. (2007) Reduction of the rate of poliovirus synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. 23rd Clinical Virology Symposium. Clearwater Beach, FL.


Post-doctorates Obtained and Professional Appointments

Ng, Tony. (2006) Postdoctoral fellow. Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT.

Shu Kin So, Stephane. (2006) Research Scientist. Applied DNA Sciences, Stony Brook, NY.

Tokarz, Rafal. (2006) Postdoctoral research scientist. Department of Epidemiology, Columbia University, New York, NY.


Software Developed

Navin, Nicholas. (2006) PROBER 2.1. PROBER is an oligonucleotide primer design software application that can generate highly specific probes for use in fluorescence in-situ hybridization (FISH) and other in-situ labeling methods. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.