1. Medical Scientist Training Program
  2. Publications

Publications

Highlighted first-author reports include (MSTP students in bold, *Co-first authors):

2023
 

  • Chesebro, AG, Mujica-Parodi, LR, Weistuch, C. Ion gradient-driven bifurcations of a multi-scale neuronal model. Chaos Solit. 2023 Feb; 167:113120.
     
  • Outhwaite IR, Singh S, Berger BT, Knapp S, Chodera JD, Seeliger MA. Death by a Thousand Cuts - Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology. bioRxiv. 16:2023.01.13.523972. 
     
  • Kaczmarzyk, Jakub R., et al. "ChampKit: a framework for rapid evaluation of deep neural networks for patch-based histopathology classification." Computer Methods and Programs in Biomedicine (2023): 107631.
     
  • Bae, Joseph; Prasanna, Prateek; Gadgeel, Shirish M; 1544P Pre-treatment CT radiomics predicts survival in chemo-immunotherapy-treated small cell lung cancer. Annals of Oncology. 33S12532022. Elsevier.
     
  • Murgas KA, Saucan E, Sandhu R. Hypergraph geometry reflects higher-order dynamics in protein interaction networks. Scientific Reports. 2022;12(1):20879.
     
  • Yan R*, Moresco P*, Gegenhuber B, Fearon DT. T cell-mediated development of stromal fibroblasts with an immune-enhancing chemokine profile. Cancer Immunol Res. 2023 May 22:CIR-22-0593. *Co-first authorship
     
  • Williams JC, Zheng ZJ, Tubiolo PN, Luceno JR, Gil RB, Girgis RR, Slifstein M, Abi-Dargham A, Van Snellenberg JX. Medial Prefrontal Cortex Dysfunction Mediates Working Memory Deficits in Patients With Schizophrenia. Biological Psychiatry: Global Open Science. doi:10.1016/j.bpsgos.2022.
     
  • Martinez, M.A.Q., Zhao, C.Z., Moore, F.E.Q., Yee, C., Zhang, W., Shen, K., Martin, B.L., and Matus, D.Q. (2023). Breaking the C. elegans invasion/proliferation dichotomy. bioRχiv.
     
  • Martinez, M.A.Q., Mullarkey, A.A., Yee, C., Zhao, C.Z., Zhang, W., Shen, K., and Matus, D.Q. (2022). Reevaluating the relationship between EGL-43 (EVI1) and LIN-12 (Notch) during C. elegans anchor cell invasion. Biology Open. 11(12):bio059668.
     
  • Torre-Healy, L. A., Kawalerski, R. R., Oh, K., Chrastecka, L., Peng, X. L., Aguirre, A. J., ... & Moffitt, R. A. (2023). Open-source curation of a pancreatic ductal adenocarcinoma gene expression analysis platform (pdacR) supports a two-subtype model. Communications Biology, 6(1), 163.
     
  • Yoo, Y. J., Wilkins, K. J., Alakwaa, F., Liu, F., Torre-Healy, L. A., Krichevsky, S., ... & Koraishy, F. M. (2023). Geographic and Temporal Trends in COVID-Associated Acute Kidney Injury in the National COVID Cohort Collaborative. Clinical Journal of the American Society of Nephrology, 10-2215.
     
  • Kobayashi S., Shieh J., Ruiz de Sabando A., Kim J., Liu Y., Zee S.Y., Prasanna P., Bialkowska A.B., Saltz J.H., Yang V.W. (2022). Deep learning-based approach for the characterization and quantification of histopathology in mouse models of colitis. PLoS One. doi: 10.1371/journal.pone.0268954.
     
  • Chen A.P., Russell G., Ashour A., Yacoub A. (2023). Acute mania in Fanconi Bickel syndrome, a case report. Research Square, https://doi.org/10.21203/rs.3.rs-2846448/v1
     
  • Chen A.P., Malgady J.M., Chen L., Shi K.W., Cheng E., Plotkin J.L., Ge S., Xiong Q. (2022). Nigrostriatal dopamine pathway regulates auditory discrimination behavior. Nature Communications, 13:5942.
     
  • Chen A.P., Ismail Z., Mann F.D., Bromet E.J., Clouston S.A., Luft B. (Accepted). Behavioral and sensory impairments in parietal-dominant Alzheimer’s disease.
     
  • Rupert, DD, Kays, M,Negris, O, Thompson, B, Clayman, ML, Mordell, L, Pendergrast, T, Bloomgarden, E, Bhayani, R, and Jain S (2023). Flattening Hierarchical Structures to Empower Women Trainee Leaders on Social Media Teams. Journal of Medical Internet Research (JMIR). 25:e47800
     
  • Rupert DD, Alvarez GV, Sinclair S, Miyara SJ, Guevara S, Shih P, and Hoey C (2023). Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report. Frontiers in Medicine. 9:1003193.
     

Co-authored publications

  • Sreenivasamurthy S, Laul M, Zhao N, Kim T, Zhu D. Current progress of cerebral organoids for modeling Alzheimer’s disease origins and mechanisms. (2022). Bioeng Transl Med, 8(2), e10378. 
     
  • Zhang Q, Yang L, Liu YH, Wilkinson JE, Krainer AR. Antisense oligonucleotide therapy for H3.3K27M diffuse midline glioma. Sci Transl Med. 2023;15(691):eadd8280. 
     
  • Mingione VR*, Paung Y*, Outhwaite IR*#, Seeliger MA#. Allosteric regulation and inhibition of protein kinases. Biochem Soc Trans. 2023 Feb 27;51(1):373-385. *=co-contribution, #=co-corresponding 
     
  • Phillips HE, Jennings RB, Outhwaite IR, Grosser S, Chandra M, Ende V, Post SG. Motivation to Impact: Medical Student Volunteerism in the COVID 19 Pandemic. Med Sci Educ. 2022 Sep 19;32(5):1149-1157. 
     
  • Zhou, Lei; Liu, Huidong; Bae, Joseph; He, Junjun; Samaras, Dimitris; Prasanna, Prateek; Token Sparsification for Faster Medical Image Segmentation. International Conference on Information Processing in Medical Imaging. 743-7542023. Springer Nature.
     
  • Liu, H., Lauzadis, J., Gunaratna, K., Sipple, E., Kaczocha, M., & Puopolo, M. (2023). Inhibition of T-Type Calcium Channels With TTA-P2 Reduces Chronic Neuropathic Pain Following Spinal Cord Injury in Rats. The Journal of Pain, S1526-5900(23)00404-2. 
     
  • Wan, L., Kral, A. J., Voss, D. & Krainer, A. R. Preclinical Screening of Splice-Switching Antisense Oligonucleotides in PDAC Organoids. bioRxiv, 2023.2003.2031.535161 (2023). 
     
  • Jeffrey M. Malgady, Alexander Baez, Kimberly Jimenez, Zachary B. Hobel, Eric M. Prager, Qiangge Zhang, Guoping Feng, Joshua L. Plotkin. "Non-synaptic alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior." bioRxiv 2022.02.07.479446
     
  • Weistuch C, Murgas KA, Zhu J, Norton L, Dill KA, Deasy JO, Tannenbaum AR. Cancer heterogeneity is defined by normal cellular trade-offs. bioRxiv. 2023:2023-04.
     
  • Schiff HC, Kogan JF, Isaac M, Czarnecki LA, Fontanini A, Maffei A. (2023) Experience-dependent plasticity of gustatory insular cortex circuits and taste preferences. Sci Adv. PMID: 36630501.
     
  • Wang Z, Moresco P, Yan R, Li J, Gao Y, Biasci D, Yao M, Pearson J, Hechtman JF, Janowitz T, Zaidi RM, Weiss MJ, Fearon DT. Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2119463119.
     
  • Medwig-Kinney, T.N., Kinney, B.A., Martinez, M.A.Q., Yee, C., Sirota, S.S., Mullarkey, A.A., Somineni, N., Hippler, J., Zhang, W., Shen, K., Hammell, C.M., Pani, A.M., and Matus, D.Q. (2022). Transcriptional regulation and repressive condensates modulate a proliferative-invasive cellular switch in vivo. bioRχiv.
     
  • Xiao, Y., Yee, C., Zhao, C.Z., Martinez, M.A.Q., Zhang, W., Shen, K., Matus, D.Q., and Hammell, C. (2023). An expandable FLP-ON::TIR1 system for precise spatiotemporal protein degradation in C. elegans. Genetics. 223(4):iyad013.
     
  • Maheshwari, R., Rahman, M.M., Drey, S., Onyundo, M., Fabig, G., Martinez, M.A.Q., Matus, D.Q., Müller-Reichert, T., and Cohen-Fix, O. (2023). A membrane reticulum, the centriculum, affects centrosome size and function in Caenorhabditis elegans. Current Biology. 33(5):791-806.e7
     
  • Smith, G.T., D.P. Radin, and S.E. Tsirka, From protein-protein interactions to immune modulation: Therapeutic prospects of targeting Neuropilin-1 in high-grade glioma. Front Immunol, 2022. 13: p. 958620.
     
  • Hwang, G. R., Yuen, J. G., Fesler, A., Farley, H., Haley, J. D., & Ju, J. (2023). Development of a 5-FU modified miR-129 mimic as a therapeutic for non-small cell lung cancer. Molecular Therapy-Oncolytics, 28, 277-292.
     
  • Bartlett EA, Yttredahl AA, Boldrini M, Tyrer AE, Hill KR, Ananth MR, Milak MS, Oquendo MA, Mann JJ, DeLorenzo C, Parsey RV. In vivo serotonin 1A receptor hippocampal binding potential in depression and reported childhood adversity. European Psychiatry. 2023, 66(1):1-9.
     
  • Narayan GA, Hill KR, Wengler K, He X, Wang J, Yang J, Parsey RV, DeLorenzo C. Does the change in glutamate to GABA ratio correlate with change in depression severity? A randomized, double-blind clinical trial. Molecular Psychiatry. 2022, 27(9):3833-3841
     
  • Achonu J, Oh K, et al. Epidemiologic patterns of adolescent idiopathic scoliosis detection and treatment in New York state. Journal of Pediatric Orthopaedics (2023) e001066.
     
  • Hakim D, Coskun AU, Maynard C, Pu Z, Rupert D, Cefalo N, Cormier M, Ahmed M, Earls J, Jennings R, Croce K, Mushtaq S, Andreini D, Conte E, Molony D, Samady H, Min JK, Stone PH. Endothelial shear stress computed from coronary computed tomography angiography: A direct comparison to intravascular ultrasound. J Cardiovasc Comput Tomogr. 2023 May-Jun;17(3):201-210. 
     
  • Hakim D, Pinilla-Echeverri N, Coskun AU, Pu Z, Olli KA, Rupert D, Maynard C, Cefalo N, Siasos G, Papafaklis MI, Kostas S, Michalis LK, Jolly S, Mehta SR, Sheth T, Croce K, Stone PH. The role of endothelial shear stress, shear stress gradient, and plaque topography in plaque erosion. Atherosclerosis. 2023 May 18;376:11-18. 
     

2022

  • Chesebro, AG. De Profundis: Oscar Wilde’s narrative of mental anguish. Hektoen Int. 2022 Winter; 14(1):hekint.org/2022/02/07/de-profundis-oscar-wildes-narrative-of-mental-anguish/.
     
  • Bae, J.; Cattell, R.; Zabrocka, E.; Roberson, J.; Payne, D.; Mani, K.; Prasanna, P. Pre-Treatment Radiomics from Radiotherapy Dose Regions Predict Distant Brain Metastases in Stereotactic Radiosurgery. In Medical Imaging 2022: Physics of Medical Imaging; SPIE, 2022.
     
  • Fassler D.J., Torre-Healy L.A., Gupta R., Hamilton A., Kobayashi S., et al. (2022) Spatial characterization of tumor-infiltrating lymphocytes and breast cancer progression. Cancers. doi: 10.3390/cancers14092148.
     
  • Kim, T.A., Syty, M. D., Wu, K., & Ge, S. (2022). Adult hippocampal neurogenesis and its impairment in Alzheimer's disease. Zoological research, 43(3), 481–496. https://doi.org/10.24272/j.issn.2095-8137.2021.479
     
  • Kim TA, Chen L, Ge S. The interplay of neurovasculature and adult hippocampal neurogenesis. Neurosci Lett. 2021 Aug 24;760:136071. 
     
  • Kim YJ, Nomakuchi T, Papaleonidopoulou F, Yang L, Zhang Q, Krainer AR. Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy. Nat Commun. 2022 May 27;13(1):2978. 
     
  • Lyczek, A.*; Berger, B.T.*; Rangwala, A.M.*; Paung, Y.; Tom, J.; Philipose, H.; Guo, J.; Albanese, S.K.; Robers, M.B.; Knapp, S.; et al. Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance. Proc Natl Acad Sci U S A 2021, 118, e2111451118 
    * Co-first author
  • Murgas, K.A., Ma, Y., Shahidi, L.K., Mukherjee, S., Allen, A.S., Shibata, D. and Ryser, M.D., 2022. A Bayesian hierarchical model to estimate DNA methylation conservation in colorectal tumors. Bioinformatics, 38(1), 22-29.
     
  • Murgas, K.A., Saucan, E. and Sandhu, R., 2021, November. Quantifying cellular pluripotency and pathway robustness through Forman-Ricci curvature. In International Conference on Complex Networks and Their Applications (pp. 616-628). Springer, Cham.
     
  • Radin D, Smith G, Moushiaveshi V, Wolf A, Bases R, Tsirka SE. (2022). Lucanthone targets lysosomes to perturb glioma proliferation, chemoresistance and stemness, and slows tumor growth in vivo. Frontiers in Oncology. 12:852940.
     
  • Rangwala, A.M.*†; Mingione, V.R.*; Georghiou, G.; Seeliger, M.A.† Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome. Biomolecules 2022, 12, 685.
    * Co-first author, † Co-corresponding author
     
  • Rangwala, A.M.†; Berger, B.T.; Robers, M.B.; Knapp, S.; Seeliger, M.A.† Resistance to kinase inhibition through shortened target engagement. Mol Cell Oncol 2022, 9, 2029999.
    † Co-corresponding author
     
  • Yuen, J. G., Marshilok, A. C., Benziger, P. T., Yan, S., Cello, J., Stackhouse, C. A., ... & Shroyer, K. R. (2022). Dry heat sterilization as a method to recycle N95 respirator masks: the importance of fit. PloS one, 17(1), e0257963.
     
  • Martinez, M.A.Q. and Matus, D.Q. (2022). CDK activity sensors: genetically encoded ratiometric biosensors for live analysis of the cell cycle. Biochemical Society Transactions. 50(3): 1081-1090.
     
  • Martinez, M.A. (2022). Do I Belong? Journal of Oncology Practice. 18(5): 378-379.
     
  • Williams JC, Tubiolo PN, Luceno JR, Van Snellenberg JX. Advancing motion denoising of multiband resting-state functional connectivity fMRI data. Neuroimage. 2022 Apr 1;249:118907. 
     
  • Wang A., Fogel A.L., Murphy M.J., Panse G, McNiff J.M., Bosenberg M., Vesely M.D., Cohen J.M., Ko C.J., King B., Damsky W., Cytokine RNA in situ hybridization permits individualized molecular phenotyping in biopsies of psoriasis and atopic dermatitis, Journal of Investigative Dermatology, Innovations (2021)
     
  • Hill KR, Gardus JD, Bartlett AE, Perlman G, Parsey RV, DeLorenzo C. Measuring brain glucose metabolism in order to predict response to antidepressant or placebo: A randomized clinical trial, NeuroImage: Clinical, Volume 32, 2021,102858.
     
  • Hill KR, Hsu DT, Taylor SF, Ogden RT, DeLorenzo C, Parsey RV. Rejection sensitivity and mu opioid receptor dynamics associated with mood alterations in response to social feedback. Psychiatry Res Neuroimaging. 2022; 324:111505.
     
  • Hill KR, Hsu DT, Taylor SF, Ogden RT, Parsey RV, DeLorenzo C. Mu Opioid Receptor Dynamics in Healthy Volunteers with a History of Childhood Maltreatment. In press: Journal of Child & Adolescent Trauma, June 2022. 
     
  • Mohammed S, Shamseddine AA, Newcomb B, Chavez RS, Panzner TD, Lee AH, Canals D, Okeoma CM, Clarke CJ, Hannun YA. Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases. Breast Cancer Res. 2021 Jul 27;23(1):76.
     
  • Rupert, Deborah D. MS, MA1; Alvarez, George V. MD2; Burdge, Eric J.3; Nahvi, Roxanna J. PhD4; Schell, Spencer M. MD5; Faustino, Francis L. MD6 Student-Run Free Clinics Stand at a Critical Junction Between Undergraduate Medical Education, Clinical Care, and Advocacy, Academic Medicine: 2022 – 97(6):824-831.
     

Other publications of note (not first author)

  • Lao, PJ, Boehme, AK, Morales, C, Laing, KK, Chesebro, AG, Igwe, K, Gutierrez, J, Gu, Y, Stern, Y, Schupf, N, Manly, JJ, Mayeux, R, Brickman, AM. Amyloid, cerebrovascular disease, and neurodegeneration biomarkers are associated with cognitive trajectories in a racially and ethnically diverse, community-based sample. Neurobiol. Aging. In Press.
     
  • Igwe, KC, Lao, PJ, Vorburger, RS, Banerjee, A, Rivera, A, Chesebro, AG, Laing, KK, Manly, JJ, Brickman, AM. Automatic quantification of white matter hyperintensities on T2-weighted fluid attenuated inversion recovery magnetic resonance imaging. Magn Reson Imaging. 2022; 85:71-79.
     
  • Rizvi B, Lao PJ, Chesebro AG, Dworkin JD, Amarante E, Beato JM, Gutierrez J, Zahodne LB, Schupf N, Manly JJ, Mayeux R, Brickman AM. Association of regional white matter hyperintensities with longitudinal Alzheimer-like pattern of neurodegeneration in older adults. JAMA Netw Open. 2021; 4(10):e2125166.
     
  • Timothy C. Borbet, Miranda B. Pawline, Xiaozhou Zhang, Sebastian Reuter, Matthew F. Wipperman, Timothy J. Maher, Jackie Li, Tadasu Iizumi, Zhan Gao, Megan Daniele, Christian Taube, Sergei B. Koralov, Anne Muller, Martin J. Blaser. Influence of the early-life gut microbiota on the immune responses to an inhaled allergen. Mucosal Immunology (in press)
     
  • Tyler PM, Bucklin ML, Zhao M, Maher TJ, Rice AJ, Ji W, Warner N, Pan J, Morotti R, McCarthy P, Griffiths A, van Rossum AMC, Hollink IHIM, Dalm VASH, Catanzaro J, Lakhani SA, Muise AM, Lucas CL. Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation. Nature Immunology. 2021; 22(9):1118-1126. 
     
  • Rosen EY, Won HH, Zheng Y, Cocco E, Selcuklu D, Gong Y, Friedman ND, de Bruijn I, Sumer O, Bielski CM, Savin C, Bourque C, Falcon C, Clarke N, Jing X, Meng F, Zimel C, Shifman S, Kittane S, Wu F, Ladanyi M, Ebata K, Kherani J, Brandhuber BJ, Fagin J, Sherman EJ, Rekhtman N, Berger MF, Scaltriti M, Hyman DM, Taylor BS, Drilon A. The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers. Nat Commun. 2022 Mar 18;13(1):1450.
     
  • Konwer, A.; Xu, X.; Bae, J.; Chen, C.; Prasanna, P. Temporal Context Matters: Enhancing Single Image Prediction With Disease Progression Representations. Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition 2022.
     
  • Soldatenko, A., Hoyt, LR., Xu, L., Calabro, S., Lewis, S.M et al. Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88. J Immunol. 2022 Feb 15;208(4):991-997.
     
  • Peterson AA, Rangwala AM, Thakur MK, Ward PS, Hung C, Outhwaite IR, Chan AI, Usanov DL, Mootha VK, Seeliger MA, Liu DR. Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Accepted at Nature Chemical Biology, 2022.
     
  • Wang Z, Moresco P, Yan R, Li J, Gao Y, Biasci D, Yao M, Pearson J, Hechtman JF, Janowitz T, Zaidi RM, Weiss MJ, Fearon DT. (2022) Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack. Proc Natl Acad Sci U S A. 119(4):e2119463119.
     
  • Kim YJ, Nomakuchi T, Papaleonidopoulou F, Yang L, Zhang Q, Krainer AR. Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy. Nat Commun. 2022 May 27;13(1):2978. 
     
  • Gu X, Richman J, Langfelder P, Wang N, Zhang S, Bañez-Coronel M, Wang HB, Yang L, Ramanathan L, Deng L, Park CS, Choi CR, Cantle JP, Gao F, Gray M, Coppola G, Bates GP, Ranum LPW, Horvath S, Colwell CS, Yang XW. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice. Neuron. 2022 Apr 6;110(7):1173-1192.
     
  • Kim YJ, Sivetz N, Layne J, Voss DM, Yang L, Zhang Q, Krainer AR. Exon-skipping antisense oligonucleotides for cystic fibrosis therapy. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114858118. 
     
  • Fassler D.J., Torre-Healy L.A., Gupta R., Hamilton A., Kobayashi S., et al. (2022) Spatial characterization of tumor-infiltrating lymphocytes and breast cancer progression. Cancers. doi: 10.3390/cancers14092148.
     
  • Gupta R., Kaczmarzyk J., Kobayashi S., Kurc T., Saltz J. (2022) AI and Pathology: Steering Treatment and Prediction Outcomes. (Book chapter, submitted to organizers)
     
  • Shieh J., Chu T.H., Liu Y., Kim J., Ruiz de Sabando A., Kobayashi S., Zee S.Y., Sheridan B.S., Bialkowska A.B., Yang V.W. (2022) KLF5 protects the intestinal epithelium against Th17 immune response in a murine colitis model. JCI Insight. doi: 10.1172/jci.insight.153488.
     
  • Ma, W.K., Voss, D.M., Scharner, J., Costa, A.S.H., Lin, K.-T., Jeon, H.Y., Wilkinson, J.E., Jackson, M., Rigo, F., Bennett, C.F., Krainer, A.R. (2022). ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth. Cancer Res. 82, 900-915.
     
  • Kim, Y.J., Sivetz, N., Layne, J., Voss, D.M., Yang, L., Zhang, Q., and Krainer, A.R. (2022). Exon-skipping antisense oligonucleotides for cystic fibrosis therapy. PNAS. 119, e2114858118.
     
  • Mingione, V.R.; Foda, Z.H.; Paung, Y.; Philipose, H.; Rangwala, A.M.; Shan, Y.; Seeliger, M.A. Validation of an Allosteric Binding Site of Src Kinase Identified by Unbiased Ligand Binding Simulations. Journal of molecular biology 2022, 167628.
     
  • Fassler DJ, Torre-Healy LA, Gupta R, Hamilton AM, Kobayashi S, Van Alsten SC, Zhang Y, Kurc T, Moffitt RA, Troester MA, Hoadley KA, Saltz J. Spatial Characterization of Tumor-Infiltrating Lymphocytes and Breast Cancer Progression. Cancers. 2022; 14(9):2148.
     
  • S. Kapse, L. Torre-Healy, R. A. Moffitt, R. Gupta and P. Prasanna, "Subtype-Specific Spatial Descriptors of Tumor-Immune Microenvironment are Prognostic of Survival in Lung Adenocarcinoma," 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI), 2022, pp. 1-5.
     
  • Mellia, Joseph A. BA∗; Basta, Marten N. MD†; Toyoda, Yoshiko MD∗; Othman, Sammy BS∗; Elfanagely, Omar MD∗; Morris, Martin P. MBE∗; Torre-Healy, Luke BS‡; Ungar, Lyle H. PhD§; Fischer, John P. MD, MPH∗ Natural Language Processing in Surgery, Annals of Surgery: May 2021 - Volume 273 - Issue 5 - p 900-908.
     
  • Sloat, S. A., Noble, L. M., Paaby, A. B., Bernstein, M., Chang, A., Kaur, T., Yuen, J., ... & Rockman, M. V. (2022). Caenorhabditis nematodes colonize ephemeral resource patches in neotropical forests. Ecology and Evolution. In press.
     
  • Mohammed S, Shamseddine AA, Newcomb B, Chavez RS, Panzner TD, Lee AH, Canals D, Okeoma CM, Clarke CJ, Hannun YA. Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases. Breast Cancer Res. 2021 Jul 27;23(1):76. 
     
  • Smith, J.J., Xiao, Y., Parsan, N., Medwig-Kinney, T.N., Martinez, M.A.Q., Moore, F.E.Q., Palmisano, N.J., Kohrman, A.Q., Chandhok Delos Reyes, M., Adikes, R.C., Liu, S., Bracht, S.A., Zhang, W., Wen, K., Kratsios, P., and Matus, D.Q. (2022). The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo. PLoS Genetics. 18(1): e1009981.
     
  • Hills-Muckey, K., Martinez, M.A.Q., Stec, N., Hebbar, S., Saldanha, J., Medwig-Kinney, T.N., Moore, F.E.Q., Ivanova, M., Morao, A., Ward, J.D., Moss, E.G., Ercan, S., Zinovyeva, A.Y., Matus, D.Q., and Hammell, C.M. (2022). An engineered, orthogonal auxin analog/AtTIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans. Genetics. 220(2): iyab174.
     
  • Gutbrod, M., Roche, B., Steinberg, J. ... Martienssen, R. (2022). Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4. Nature Communications.
     
  • Moeller SJ, Gil R, Weinstein JJ, Baumvoll T, Wengler K, Fallon N, Van Snellenberg JX, Abeykoon S, Perlman G, Williams J, Manu L, Slifstein M, Cassidy CM, Martinez DM, Abi-Dargham A. Deep rTMS of the insula and prefrontal cortex in smokers with schizophrenia: Proof-of-concept study. NPJ Schizophr. 2022 Feb 25;8(1):6.
     
  • Turner MP, Zhao Y, Abdelkarim D, Liu P, Spence JS, Hutchison JL, Sivakolundu DK, Thomas BP, Hubbard NA, Xu C, Taneja K, Lu H, Rypma B. "Altered linear coupling between stimulus-evoked blood flow and oxygen metabolism in the aging human brain." Cerebral Cortex. 2022
     
  • Kanan Y, Hackett SF, Taneja K, Khan M, Campochiaro PA. "Oxidative stress-induced alterations in retinal glucose metabolism in Retinitis Pigmentosa." Free Radical Biology and Medicine. 2022
     
  • Patel K, Taneja K, Mohamed A, Batchu S, Hsiung H, Mott C, Tornberg H, Patel UK. "An Analysis of Epidemiological Factors in Heart Failure Outcomes." Cureus. 2022
     
  • Damsky W., Wang A., Kim D.J., Young B.D., Singh K., Murphy M.J., Clark A., Ayasun R., Ryu C., McGeary M.K., Odell I.D., Fazzone-Chettiar R., Pucar D., Homer R., Gulati M., Miller E.J., Bosenberg M., Flavell R.A., King B., Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis, Nature Communications (2022).
     
  • Catherine Blaha, Gopalakrishnan Ramakrishnan, Sang-Min Jeon, Hyunsoo Rho, Prashanth Bhaskar, Soeun Kang, Veronique Nogueira, Alexander R. Terry, Alexandre F. Aissa, Maxim V. Frolov, Krushna C. Patra, R. Brooks Robey, and Nissim Hay. A novel Hexokinase 2 non-catalytic activity promotes EMT and metastasis. Nature Communications, 13899 (2022).
     
  • Francisco, D., Wang, Y., Marshall, C., Conway, M., Addison, K. J., Billheimer, D., Kimura, H., Numata, M., Chu, H. W., Voelker, D. R., Kraft, M., & Ledford, J. G. (2022). Small Peptide Derivatives Within the Carbohydrate Recognition Domain of SP-A2 Modulate Asthma Outcomes in Mouse Models and Human Cells. Frontiers in immunology, 13, 900022. 
     
  • Iannuzo N, Insel M, Marshall C, Pederson WP, Addison KJ, Polverino F, Guerra S, Ledford JG. CC16 Deficiency in the Context of Early-Life Mycoplasma pneumoniae Infection Results in Augmented Airway Responses in Adult Mice. Infect Immun. 2022 Feb 17;90(2):e0054821. 
     
  • Mondal, C., Gacha-Garay, M. J., Larkin, K., Adikes, R., Di Martino, J., Chien, C. C., Fraser, M., Eni-aganga, I., Agulla-Pascual, E., Ozbek, U., Naba, A., Gaitas, A., Fu, T. M., Upadhyayula, S., Betzig, E., Matus, D., Martin, B. L., Bravo-Cordero, J. J. A Proliferative to Invasive Switch is Mediated by srGAP1 Downregulation Through the Activation of TGFβ2 Signaling. Cell Reports. 2022; In Press.

2021

  • Amin, J. B., Gochman, A., He, M., Certain, N., & Wollmuth, L. P. (2021). NMDA Receptors Require Multiple Pre-opening Gating Steps for Efficient Synaptic Activity. Neuron, 109(3), 488–501.e4.
     
  • Amin, J. B., Moody, G. R., & Wollmuth, L. P. (2021). From bedside-to-bench: What disease-associated variants are teaching us about the NMDA receptor. The Journal of Physiology, 599(2), 397–416.
     
  • Carter, J.A.*, Freedenberg, A.T.*, Romeiser, J.L., Talbot, L.R., Browne, N.J., Cosgrove, M.E., Shevik, M.E., Generale, L.M., Rago, M.G., Caravella, G.A., Ahmed, T., Mamone, L.J., and Bennett-Guerrero, E. for The Stony Brook Medicine COVID Plasma Trial Group. "Impact of serological and PCR testing requirements on the selection of COVID-19 convalescent plasma donors." Transfusion 61(5):1461-1470 (2021) *Equal Contribution.
     
  • Chen, A.P., Chen, L., Kim, T.A., Xiong, Q. Integrating the Roles of Midbrain Dopamine Circuits in Behavior and Neuropsychiatric Disease. Biomedicines, 9, 647 (2021). https://doi.org/10.3390/biomedicines9060647.
     
  • Cheng DK, Oni TE, Thalappillil JS, Park Y, Ting HC, Alagesan B, Prasad NV, Addison K, Rivera KD, Pappin DJ, Van Aelst L, Tuveson DA. Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2016904118. doi: 10.1073/pnas.2016904118. PMID: 34021083; PMCID: PMC8166058.
     
  • Guinn, M.T., Coraci, D., Guinn, L., & Balázsi, G. (2021). Reliably Engineering and Controlling Stable Negative
    Feedback Optogenetic Gene Circuits in Mammalian Cells. Journal of Visualized Experiments (JoVE), Invited Article, Accepted.
     
  • Hill K, Gardus J, Bartlett E, Perlman G, Parsey R, DeLorenzo C. Fully quantitative pretreatment brain metabolism does not predict depression response to Escitalopram or Placebo, submitted to NeuroImage: Clinical.
     
  • Kim, T. A., Chen, L., Ge, S. The Interplay of Neurovasculature and Adult Hippocampal Neurogenesis. Neuroscience letters, 136071. (2021) doi: 10.1016/j.neulet.2021.136071; PMID: 34147540.
     
  • Kobayashi S., Saltz JH, Yang VW. (2021). State of machine and deep learning in histopathological applications in digestive diseases. World Journal of Gastroenterology. doi: 10.3748/wjg.v27.i20.2545. (Review)
     
  • Li M., Patel H.V., Cognetta A.B., Smith T.C., Mallick I., Cavalier J.F., Canaan S., Aldridge B.B., Cravatt B.F., Seeliger J.C. (2021) A Competitive Activity-Based Protein Profiling Platform Yields Cell Wall Synthesis Inhibitors Active Against Replicating and Non-Replicating Mycobacterium Tuberculosis. BioRxiv; doi: https://doi.org/10.1101/2021
     
  • Lyczek, A*., Berger, B.T*., Rangwala, A.M.*, Paung, Y., Tom, J., Philipose, H., Guo, J., Albanese S.K., Robers, M.B., Knapp, S., Chodera, J.D., Seeliger, M.A. "Mutation in Abl kinase with altered drug binding kinetics indicates novel mechanism of imatinib resistance" (Submitted to PNAS)
    *Denotes equal contribution
     
  • K.A. Murgas, E. Saucan, R. Sandhu. Quantifying Cellular Pluripotency through Network Curvature. IEEE Conference on Decision and Control 2021. Submitted.
     
  • Talbot LR, Romeiser JL, Spitzer ED, Gan TJ, Singh SM, Fries BC, Bennett-Guerrero E. Prevalence of IgM and IgG antibodies to SARS-CoV-2 in health care workers at a tertiary care New York hospital during the Spring COVID-19 surge. Perioper Med (Lond). 2021 Mar 2;10(1):7. doi: 10.1186/s13741-021-00177-5
     
  • *Kawalerski R, *Torre-Healy L, Oh K, ... Moffitt RA, pdacR: Curation and analysis of pancreatic ductal adenocarcinoma gene expression data supports a two-subtype model and enables community exploration. Submitted July 2021 - Nature Cancer
     
  • John C. Williams, Philip N. Tubiolo, Jacob R. Luceno, and Jared X. Van Snellenberg. Advancing motion denoising of multiband resting-state functional connectivity fMRI data. (In revision).
     
  • Yu AT, Berasain C, Bhatia S, Rivera K, Liu B, Rigo F, Pappin DJ, Spector DL. PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR. Elife. 2021 May 18;10:e68263. doi: 10.7554/eLife.68263. Epub ahead of print. PMID: 34002693.

2020

  • Amin JB, Gochman A, He M, Certain N, Wollmuth LP. NMDA Receptors Require Multiple Pre-opening Gating Steps for Efficient Synaptic Activity. Neuron. 2020 Nov 23:S0896-6273(20)30887-4. doi: 10.1016/j.neuron.2020.11.009. Epub ahead of print. PMID: 33264592.
     
  • Amin, J. B., Moody, G. R., & Wollmuth, L. P. (2020). From bedside-to-bench: What disease-associated variants are teaching us about the NMDA receptor. The Journal of Physiology, 10.1113/JP278705. Advance online publication.

  • Arreguin AJ, Colognato H. “Brain dysfunction in LAMA2-related Congenital Muscular Dystrophy: lessons from human case reports and mouse models” Frontiers in Molecular Neuroscience. 13 (2020):18.

  • Bae, J.; Kapse, S.; Singh, G.; Phatak, T.; Green, J.; Madan, N.; Prasanna, P. Predicting Mechanical Ventilation Requirement and Mortality in COVID-19 Using Radiomics and Deep Learning on Chest Radiographs: A Multi-Institutional Study. In submission. arXiv:2007.08028 [cs, eess, q-bio] 2020.

  • Baez A, Van Brunt T, Moody G, Wollmuth LP, Hsieh H. Voltage dependent allosteric modulation of IPSCs by benzodiazepines. Brain Res. 2020 Jun 1;1736:146699. doi: 10.1016/j.brainres.2020.146699. Epub 2020 Feb 3. PMID: 32027866.

  • Chan, K.*, J. Nestor*, T. S. Huerta, N. Certain, G. Moody, C. Kowal, P. T. Huerta, B. T. Volpe, B. Diamond and L. P. Wollmuth (2020) Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory. Nature Communications, 11:1403(2020). (PMCID: PMC7075964).   *Authors contributed equally.

  • Zoodsma, J. D.*, K. Chan*, A. A. Bhandiwad, D. Golann, G. Liu, S. Syed, A. Napoli, H. Burgess, H. Sirotkin, and L. P. Wollmuth. (2020) A model to study NMDA receptors in early nervous system development. The Journal of Neuroscience. 40:3631-3645. (PMCID: PMC7189761).    *Authors contributed equally.

  • Fassler D*, Abousamra S*, Gupta R, Chen C, Zhao M, Paredes D, Batool SA, Knudsen B, Escobar-Hoyos L, Shroyer KR, Samaras D, Kurc T, and Saltz J. Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images. Diagn Pathol. – accepted July 2020.

  • Guinn, M.T., Wan, Y., Levovitz, S., Yang, D, Rosner, M., & Balázsi, G. (2020). Observation and Control of Gene Expression Noise: Barrier Crossing Analogies between Drug Resistance and Metastasis. Frontiers in Genetics. Accepted.

  • Kéry R., Chen APF, Kirschen GW. (2020). Genetic targeting of astrocytes to combat neurodegenerative disease. Neural Regeneration Research. 15(2):199-211.
     
  • Kim CK, Saxena M, Maharjan K, et al. Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells. CMGH. 2020;9(4):587-609. PMID: 31778829
     
  • Kirschen GW, Wood LF, Semenyuk N. A Practical Approach to Congenital Urogenital Anomalies in Female Pediatric Patients. Pediatr Ann. 2020 Apr 1;49(4):e188-e195. doi: 10.3928/19382359-
    20200323-02. PMID: 32275764.

  • Wohl A, Kirschen GW. Reading the Child Within: How Bibliotherapy Can Help the Victim of Child Sexual Abuse.  J Child Sex Abus. 2020 May-Jun;29(4):490-498. doi: 10.1080/10538712.2019.1630882.
    Epub 2019 Aug 26. PMID: 31448980

  • *Kirschen GW†, Yang C-H†, Di Antonio A†, Varma P, Hsieh J, Ge S. “Circuit integration initiation of new hippocampal neurons in the adult brain. Cell Rep. 2020 Jan 28;30(4):959-968.e3. doi: 10.1016/j.celrep.2019.12.084. PMID: 31995766.  *Authors contributed equally.
     
  • Kirschen GW, Altieri MS, Yelika S, Bates AT, Schnur J, Docimo S, Spaniolas K, Zhu C, Yang J, Talamini M, Pryor AD, Sbayi S. Does the adoption of an emergency general surgery service model influence volume of cholecystectomies at a tertiary care center. Surg Endosc. 2020 Jul;34(7):3064-3071. doi: 10.1007/s00464-019-07052-x. Epub 2019 Aug 9. PMID: 31399949.

  • Kirschen GW, Singer DD, Thode HC Jr, Singer AJ. Relationship between body temperature and heart rate in adults and children: A local and national study. Am J Emerg Med. 2020 May;38(5):929-933. doi:
    10.1016/j.ajem.2019.158355. Epub 2019 Jul 18. PMID: 31345594

  • Kirschen GW, Jones JJ, Hale L. The Impact of Sleep Duration on Performance Among Competitive Athletes: A Systematic Literature Review. Clin J Sport Med. 2020 Sep;30(5):503-512. doi: 10.1097/JSM.0000000000000622. PMID: 29944513

  • Lewis, S.M., Strano-Paul, L.A. A COVID Service-Learning Initiative: Emotional Support Calls for the Geriatric Population. J Am Geriatr Soc. 2020 Dec 31. doi: 10.1111/jgs.17003.

  • Martinez, M.A.Q. and Matus, D.Q. (2020). Auxin-mediated protein degradation in Caenorhabditis elegans. Bio-protocol. 10(8): e3589.
     
  • Martinez, M.A.Q., Kinney, B.A., Medwig-Kinney, T.N., Ashley, G., Ragle, J.M., Johnson, L., Aguilera, J., Hammell, C.M., Ward, J.D., and Matus, D.Q. (2020). Rapid degradation of Caenorhabditis elegans proteins at single-cell resolution with a synthetic auxin. G3: Genes, Genomes, Genetics. 10(1): 267-280. Cover Jan. 2020.

  • *Motley MP, Diago-Navarro E, Banerjee K, Inzerillo S, Fries BC. The Role of IgG Subclass in Antibody- Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae. mBio. 2020; 8;11(5):e02059-20. PubMed: 32900809; PubMed Central: PMC7482069

  • Pillai RLI, Bartlett EA, Ananth MR, Zhu C, Yang J, Hajcak G, Parsey RV, DeLorenzo C. Examining the underpinnings of loudness dependence of auditory evoked potentials with positron emission tomography. NeuroImage 213 (2020): 116733.
     
  • Pillai RLI. We all need a little TLC: an argument for an increased role of Child Life Services in patient care and medical education. Hosp Pediatr. 2020 Oct;10(10):913-917. doi: 10.1542/hpeds.2020-0119. Epub 2020 Sep 4. PMID:
    32887731.
     
  • Radin DP, Tsirka SE. Interactions between Tumor Cells, Neurons, and Microglia in the Glioma Microenvironment. Int J Mol Sci. 2020 Nov 11;21(22):8476.

  • Rupert, D, Nowlan, A, Tam, O, and Hammell, M (2020). Ten simple rules for running a
    successful women-in-STEM organization on an academic campus. PLOS Computational
    Biology.     DOI: .10.1371/journal.

  • Williams, JC and Van Snellenberg, JX. Motion denoising of multiband resting state functional connectivity MRI data: An improved volume censoring method. bioRxiv 860635; doi:https://doi.org/10.1101/860635.

  • Chang, K.C., Diermeier, S.D.*, Yu, A.T.*, Brine, L.D., Russo, S., Bhatia, S., Alsudani, H., Kostroff, K., Bhuiya, T., Brogi, E., Bennett, C.F., Rigo, F., Spector, D.L.. Assessing the role of the long non-coding RNA MaTAR25 in mammary tumor progression. Nature Communications. 2020, Oct; Pub Status: Accepted.

2019   

  • Humpton TJ*, Alagesan B*, DeNicola GM, Lu D, Yordanov GN, Leonhardt CS, Yao MA, Alagesan P, Zaatari MN, Park Y, Skepper JN, Macleod KF, Perez-Mancera PA, Murphy MP, Evan GI, Vousden KH, Tuveson DA. Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer. Cancer Discovery 2019; 9(9):1268-1287. PMID: 31263025 * co-first author

  • Carter, J.A., Gilbo, P., and Atwal, G.S. (2019) “IMPRES does not reproducibly predict response to immune checkpoint blockade therapy in metastatic melanoma.” Nature Medicine 25(12):1833-1835

  • Carter, J.A., Preall, J., and Atwal, G.S. (2019) “Bayesian inference of allelic inclusion rates in the human T cell receptor repertoire.” Cell Systems 9(5):475-482

  • Carter, J.A., Preall, J., Grigaityte, K., Goldfless, S.J., Jeffery, E., Briggs, A.W., Vigneault, F., and Atwal, G.S. (2019) “Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity.” Frontiers in Immunology 10:1516

  • Guinn, M.T. & Balazsi, G. (2019). A new resource for future and current quantitative biologists. The Quarterly Review of Biology, 94, Issue 4, December 2019, https://www.journals.uchicago.edu/doi/abs/10.1086/706383.

  • Guinn, M.T. & Balazsi, G. (2019). Noise-Reducing Optogenetic Negative-Feedback Gene Circuits in Human Cells. Nucleic Acids Research, gkz556, https://doi.org/10.1093/nar/gkz556

  • Kirschen GW, Semenyuk N. “Primary amenorrhea, aplastic uterus, and a functional vagina: A rare case of Mayer-Rokitansky-Küster-Hauser syndrome.” 2019. Case Rep Obstet Gynecol. 3409548: 1-4. PMID: 31275680.

  • Kirschen GW, Kim E, Adsumelli RSN. “Dexmedetomidine-induced massive diuresis in a patient undergoing spinal fusion surgery: a case report and synthesis of the literature.” 2019. A A Pract. 12(4):112-114. PMID: 30085933.

  • Kirschen GW*, Wang J*, Shen J*, Jessberger S, Gu Y, Xiong Q, Ge S. “Lateral dispersion is required for circuit integration of newly generated dentate granule cells.”  Nature Communications.

  • Kirschen GW, Ge S. Young at heart: Insights into hippocampal neurogenesis in the aged brain. Behav Brain Res. 2019 Sep 2;369:111934. doi: 10.1016/j.bbr.2019.111934. Epub 2019 May 1. PMID: 31054278

  • *Motley MP, Banerjee K, Fries BC. Monoclonal antibody-based therapies for bacterial infections. Curr Opin Infect Dis. 2019; 32(3):210-6. PubMed: 30950853; PubMed Central: PMC7050834.

  • Pillai RLI, Butchart L, Hill KR, Lazarus Z, Patel R, Yan LE, Kenyon LJ, Post SG. You’re Not Alone: Sharing of Anonymous Narratives to Destigmatize Mental Illness in Medical Students and Faculty. Academic Psychiatry 44(2) (2019): 223-226.

  • Pillai RLI, Huang C, LaBella A, Zhang M, Yang J, Trivedi M, Weissman M, McGrath P, Fava M, Kurian B,Cooper C, McInnis M, Oquendo MA, Pizzagalli DA, Parsey RV, DeLorenzo C. Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response. J Affect Disord. 2019 Sep 1;256:8-16. doi: 10.1016/j.jad.2019.05.055. Epub 2019 May 28. PMID: 31158720.

  • Pillai RL, Zhang M, Yang J, Mann JJ, Oquendo MA, Parsey RV, DeLorenzo C. Molecular connectivity disruptions in males with major depressive disorder. J Cereb Blood Flow Metab. 2019 Aug;39(8):1623-1634. doi: 10.1177/0271678X18764053. Epub 2018 Mar 9. PMID: 29519187

  • Rupert, D, Jones, T, and Young, R (2019). Man with long-standing, well controlled multiple sclerosis presents with two episodes of acute psychosis. Psychiatric Annals. 49(1): 33-35.

  • N. Schwartz, I. Mileva, M. Gurevich, J. Snider, Y. Hannun, L. Obeid. 2019. Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue. Prostaglandins & Other Lipid Mediators. 141: 40-48.

  • Singleton CD, Humby MS, Yi HA, Rizzo RC, Jacobs A. Identification of Ebola Virus Inhibitors Targeting GP2 Using Principles of Molecular Mimicry. J Virol. 2019 Jul 17;93(15):e00676-19.
    PMID: 31092576 PMCID: PMC6639268

2018

  • Amin, J.B. Leng X., Gochman A., Zhou H.X. Wollmuth L.P. (2018). “A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca2+ permeability” Nature Communications.
     
  • J. Amin and L.P. Wollmuth (2018). A swiss army knife for targeting NMDA receptors (2018). Elife.
     
  • Carter, J.A., Preall, J.B., Grigaityte, K., Goldfless, S.J., Briggs, A.W., Vigneault, F., and Atwal, G.S. (2018) “T-cell receptor αβ chain pairing is associated with CD4+ and CD8+ lineage specification.” bioRxiv.

  • Cheng D, Tuveson D. Kras in Organoids. Cold Spring Harb Perspect Med. 2018;8(10):a031575. Published 2018 Oct 1. doi:10.1101/cshperspect.a031575

  • He P, Yang JW, Yang VW, Bialkowska AB. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. 2018
     
  • Kim CK, Yang VW, Bialkowska AB. (2017). The role of intestinal stem cells in epithelial regeneration following radiation-induced gut injury. Current Stem Cell Reports.
     
  • Sinha, R.*, Kim, Y. J.*, Nomakuchi, T., Sahashi, K., Hua, Y., Rigo, F., ... & Krainer, A. R. (2018). Antisense oligonucleotides correct the familial dysautonomia splicing defect in IKBKAP transgenic mice. Nucleic Acids Research.
     
  • Kirschen GW, Kery R, Liu H, Ahamad A, Chen L, Akmentin W, Kumar R, Levine J, Xiong Q, Ge S. “Genetic dissection of neuro-glio-vascular machinery in the adult brain.” 2018. Mol Brain.
     
  • Miyauchi JT, Caponegro M, Chen D, Choi M, Li M, Tsirka SE. (2018) Deletion of neuropilin 1 from microglia or bone marrow-derived macrophages slows glioma progression. Cancer Research.
     
  • N. Schwartz, R. Linzer, J. Truman, M. Gurevich, Y. Hannun, C. Senkal, L. Obeid. 2018. Decreased ceramide underlies mitochondrial dysfunction in Charcot-Marie-Tooth 2F. FASEB.
     
  • Siller SS, Sharma H, Li S, Holdener BC, Holtzman MJ, Winuthayanon W, Colognato H, Li F, Takemaru K. 2018. The Distal Appendage Protein CEP164 Coordinates Multiple Steps of Airway Multicilia Formation. PLoS Genetics.

2017

  • Gregory Kirschen, Jia Shen, Mu Tian, Bryce Schroeder, Jia Wang, Guoming Man, Song Wu, and Shaoyu Ge. Active dentate granule cells encode experience to promote the addition of adult-born hippocampal neurons. Journal of Neuroscience, 2017.
  • Kirschen GW, Lane DS, Messina CR, Fisher PR. “Do they Practice What We Preach: Findings from over a Decade of Breast Imaging CME.” 2017. Breast J. ePub ahead of print. PMID: 28585709.
  • *Kirschen GW*, Shen J*, Tian M, Schroeder B, Wang J, Man G, Wu S, Ge S. “Active dentate granule cells encode experience to promote the addition of adult-born hippocampal neurons. 2017. J Neurosci, 37(18): 461-4678. PMID: 28373391.
  • *Kirschen GW, Liu H, Lang T, Liang X, Ge S, Xiong Q. “The radial organization of neuronal primary cilia is acutely disrupted by seizure and ischemic brain injury.” 2017. Front Biol (Beijing), 12(2): 124-138. PMID: 28473847.
  • Roth, E. and M.A. Frohman, Roles for Phospholipase D in breast cancer. Advances in Biological Regulation, Vol 67, 2017.
  • Schroeder, Bryce, Zhen H. Zhu, Changliang Guo, Shu Jia. Engineering and Optimization of Quasi-Nondiffracting Helicon-Like Beams With an Evolutionary Algorithm. IEEE Photonics Journal, 2017

2016

  • Adada, M., Luberto, C., & Canals, D. (2016). Inhibitors of the sphingomyelin cycle: Sphingomyelin synthases and sphingomyelinases. Chem Phys Lipids, 197, 45-59. doi: 10.1016/j.chemphyslip.2015.07.008
  • Aleem et al. Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles, Cell Chemical Biology (2016), In Press, http://dx.doi.org/10.1016/j.chembiol.2016.07.017
  • Bhagwat AS, Roe JS, Mok BYL, Hohmann AF, Shi J, Vakoc CR Cell Reports. 2016, 15(3):519-530 BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements
  • Carter, J.A.*, Hyland, C.*, Steele, R.E., and Collins, EMS. (2016) Dynamics of Mouth Opening in Hydra. Biophysical Journal 110(5): 1191-1201. http://dx.doi.org/10.1016/j.bpj.2016.01.008 (*Equal contribution)
  • Cleary, C., et al. Biological Features of Human Papillomavirus-related Head and Neck Cancers Contributing to Improved Response. Clinical Oncology (2016).
  • Kuruvilla JG*, Kim CK*, Ghaleb AM, Bialkowska AB, Kuo CJ, Yang VW. (2016). Krüppel-like factor 4 modulates development of BMI1(+) intestinal stem cell-derived lineage following -radiation-induced gut injury in mice. Stem Cell Reports. 6(6):815-24. PMID: 27237377. #Co-first authors
  • Rhee S*, Kirschen GW*, Gu Y, Ge S. (2016). Depletion of primary cilia from mature dentate granule cells impairs hippocampus-dependent memory. Sci Rep. 2016 Sep 28;DOI:10.1038/srep34370. PMID: 27678193 *These authors contributed equally to this work.
  • Kirschen GW, Di Antonio A, Ge S. Neurobiology & Physiology of Hippocampal Neurogenesis: Physiology & Plasticity. Adult Neurogenesis in the Hippocampus: Health, Psychopathology, and Brain Disease. Academic Press & Elsevier, 2016. https://www.sciencedirect.com/science/article/abs/pii/B9780128019771000027?via%3Dihub
  • Kirschen GW, Lane DS, Messina CR. “Assessing the Perceived Utility and Impact of a Continuing Medical Education Activity in Family Medicine 2016.” Family Doctor, 4(3): 30-32.
  • McGillick, B.E & Kumaran, D & Vieni, C, Swaminathan, S. Beta-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.. Biochemistry. 2016, Jan; 55(7): 1091–1099.
  • Zhou,Y. & McGillick, B.E., & Teng, Y.G., & Haranahalli, K., & Ojima, I., & Swaminathan, S., & Rizzo, R.C. Identification of Small Molecule Inhibitors of Botulinum Neurotoxin Serotype E via Footprint Similarity. Bioorganic and Medicinal Chemistry. 2016, Jul
  • Miyauchi JT, Chen D, Choi M, Nissen JC, Shroyer KR, Djordevic S, Zachary IC, Selwood D, Tsirka SE. (2016) Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression. Oncotarget. 7(9): 9801-9814.
  • Lewis CS*, Torres L*, Miyauchi JT*, Rastegar C, Patete JM, Smith JM, Wong SS, Tsirka SE. (2016) Absence of Cytotoxicity towards Microglia of Iron Oxide (α-Fe2O3) Nanorhombohedra. Toxicology Research. 5:  836-847.
  • **Lu J, Tucciarone J*, Padilla N, He M, Gordon JA, Huang ZJ. Directional inhibitory control of pyramidal neuron subnetworks by chandelier cells (submitted to Nature Neuroscience).
    # these authors contributed equally to the work
  • **He M, Tucciarone J, Lee SH, Nigro M, Kim Y, Levine JM, Kelly SM, Krugikov I, Wu P, Chen Y, Gong Y, Hou Y, Rudy B, Osten P, Huang J. Strategies and tools for the combinatorial targeting of GABAergic neurons in mouse neocortex. Neuron. 2016. Sept 21: (91): 1-16.
  • **Stephenson-Jones M, Yu K, Ahrens S, Tucciarone JM, van Huijstee A, Mejia LA, Penzo MA, Li B. A basal ganglia circuit for evaluating action outcomes. 2016. Nature. (accepted in press)
  • **Karnani, MM, Jackson J, Ayzenshtat I, Tucciarone J, Manoocheri K, Snider WG, Yuste R. Cooperative subnetworks of molecularly similar interneurons in mouse neocortex. Neuron. 2016. Mar 23: (90)1: 86-100.
  • Pillai, Rajapillai LI and Tipre, Dnyanesh N. "Metabotropic glutamate receptor 5–a promising target in drug development and neuroimaging." European journal of nuclear medicine and molecular imaging 43.6 (2016): 1151-1170.
  • Motley MP, Madsen DH, Jürgensen HJ, Spencer DE, Szabo R, Holmbeck K, Flick MJ, Lawrence DA, Castellino FJ, Weigert R, & Bugge TH. 2016. A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo. Blood. 127(9):1085-96
  • Nomakuchi T, Rigo F, Aznarez I, Krainer AR. Antisense-oligonucleotide-directed inhibition of nonsense-mediated mRNA decay. Nature Biotechnology
  • Nemajerova A, Kramer D,* Siller SS,* Herr C,* Shomroni O, Pena T, Gallinas Suazo C, Glaser K, Wildung M, Steffen H, Sriraman A, Oberle F, Wienken M, Hennion M, Vidal R, Royen B, Alevra M, Schild D, Bals R, Donitz J, Riedel D, Bonn S, Takemaru K, Moll UM, Lize M. (2016). TAp73 is a central transcriptional regulator of airway multiciliogenesis." Genes Dev 30(11): 1300-1312.  *Authors contributed equally
  • Shamseddine AA, Clarke CJ, Carroll B, Airola MV, Rella A, Obeid LM, Hannun YA. P53-dependent upregulation of neutral sphingomyelinase-2 is required for doxorubicin-induce growth arrest. Cell death and disease 6 e1947
  • Clarke CJ, Shamseddine AA, Jacob JJ, Burns TA, Hannun YA. ATRA transcriptionally induces nSMase2 through CBP/p-300 mediated histone acetylation.  Journal of Lipid Research. 57:5
  • Werneburg, GT, Chauhan, H, Henderson, NS, & Thanassi, DG (2016). MP24-04 THE UROPATHOGENIC ESCHERICHIA COLI PILUS USHER CONTROLS PROTEIN INTERACTIONS VIA DOMAIN MASKING AND IS FUNCTIONAL AS AN OLIGOMER. The Journal of Urology, 195(4), e271 (abstract).

2015

  • Adada, M. M., Canals, D., Jeong, N., Kelkar, A. D., Hernandez-Corbacho, M., Pulkoski-Gross, M. J.,  Obeid, L. M. (2015). Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion. FASEB J, 29(11), 4654-4669. doi: 10.1096/fj.15-274340
  • Aleem SU, Craddock BP, Miller WT. (2015). Constitutive Activity in an Ancestral Form of Abl Tyrosine Kinase. PLoS One. Jun 19;10(6):e0131062. doi: 10.1371/journal.pone.0131062. eCollection 2015. PMID: 26090675
  • Bhagwat AS, Vakoc CR Trends in Cancer. 2015, 1(1):53-65 Targeting Transcription Factors in Cancer.
  • Foda ZH, Shan Y, Kim ET, Shaw DE, Seeliger MA. (2015). A dynamically coupled allosteric network underlies binding cooperativity in Src kinase. Nat Commun. Jan 20;6:5939. doi: 10.1038/ncomms6939. PMID: 25600932
  • Guja KE, Schildbach JF. 2015. Completing the specificity swap: single-stranded DNA recognition by F and R100 TraI relaxase domains. Plasmid. PMID: 25841886. *Featured on issue cover.
  • Ehrhardt, K.*, Guinn, M. T.*, Quarton, T., Zhang, M., & Bleris, L. (2015). Reconfigurable hybrid interface for molecular marker diagnostics and in-situ reporting. Biosensors and Bioelectronics, Volume 74, 15 December 2015, Pages 744-750, ISSN 0956-5663, .doi.org/10.1016/j.bios.2015.07.035. (*equal contribution)
  • Levit NA, Sellitto C, Wang HZ, Li L, Srinivas M, Brink PR, White TW. (2015). Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine. J Invest Dermatol. Apr;135(4):1033-42. doi: 10.1038/jid.2014.408. Epub 2014 Sep 17. PMID: 25229253
  • Torres L, Danver J, Ji K, Miyauchi JT, Chen D, Anderson ME, West BL, Robinson JK, Tsirka SE. (2015) Dynamic microglial modulation of spatial learning and social behavior. Brain Behav Immun. http://dx.doi.org/10.1016/j.bbi.2015.09.001
  • Roth, E., Cao, J., Li, Y., Kuscu, C., Banach, A., Zhang, Q., Pulkoski-Gross, A., Kim, D., Liu, J. miR-181 suppresses metastasis via MMP14. Aging 7, (2015).
  • Roth, E., et al. microRNA-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14. Cancer Res.75, 2674–2686 (2015).
  • Schroeder, Bryce and Shu Jia. (2015). Frequency analysis of a self-bending point spread function for 3D localization-based optical microscopy. Opt. Lett. 40, 3189-3192.
  • Siller SS,* Burke MC,* Li FQ, Takemaru K. (2015). Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells. Cell Cycle 14(19): 3163-3172.  *Authors contributed equally.
  • Shamseddine AA, Airola MV, Hannun YA. (2015). Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes. Adv Biol Regul. Jan;57:24-41. doi: 10.1016/j.jbior.2014.10.002. Epub 2014 Oct 27. PMID: 25465297
  • Werneburg GT, Henderson NS, Portnoy EB, Sarowar S, Hultgren SJ, Li H, Thanassi DG. (2015). The pilus usher controls protein interactions via domain masking and is functional as an oligomer. Nat Struct Mol Biol. Jun 8. doi: 10.1038/nsmb.3044. [Epub ahead of print] PMID: 26052892
  • Yeku O, Slovin SF. (2015). Metabolism and pharmacokinetics of radium-223 in prostate cancer. Expert Opin Drug Metab Toxicol. 2015 May;11(5):843-9. doi: 10.1517/17425255. 1021332. Epub 2015 Mar 4. PMID: 25740232

2014

  • Perry DM*, Newcomb B*, Adada M, …, Obeid LM, Hannun YA. (2014) Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway. J. Biological Chemistry 289:22401-12. * co-first authors
  • Bhagwat AS, Vakoc CR. A New Bump in the Epigenetic Landscape. Molecular Cell 2014; 53:857-858 PMID: 24656126
  • Burke MC, Li FQ, Cyge B, Arashiro T, Brechbuhl HM, Chen X, Siller SS, Weiss MA, O'Connell CB, Love D, Westlake CJ, Reynolds SD, Kuriyama R, Takemaru K. (2014). Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation. J Cell Biol. Oct 13;207(1):123-37. doi: 10.1083/jcb.201406140. PMID: 25313408
  • Schiebel J*, Chang A*, Shah S, … Knudson SE, Bommineni GR, Walker SG, Slayden RA, Sotriffer CA, Tonge PJ, Kisker C. (2014) Rational Design of Broad-Spectrum Antibacterial Activity based on a Clinically Relevant Enoyl-ACP Reductase Inhibitor. Journal of Biological Chemistry Jun 6;289(23):15987-6005 PMID: 24739388
  • Foda ZH, Seeliger MA. (2014). Kinase inhibitors: an allosteric add-on. Nat Chem Biol. Oct;10(10):796-7. doi: 10.1038/nchembio.1630. Epub 2014 Sep 7. No abstract available. PMID: 25195010
  • Griffen TC, Maffei A.GABAergic synapses: their plasticity and role in sensory cortex. Front Cell Neurosci. 2014 Mar 26;8:91. doi: 10.3389/fncel.2014.00091. PMID: 24723851
  • Kazi, R,Dai J, Sweeney C, Zhou HX, Wollmuth LP (2014) Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents. Nature Neuroscience. 17(7):914-22
  • Levit NA, Sellitto C, … White TW. (2014) Aberrant Connexin26 Hemichannels Underlying Keratitis-Ichthyosis-Deafness Syndrome are Potently Inhibited by Mefloquine. J. Investigatory Dermatology In press, Sep 17.
  • Premsrirut, P.K., Teruya-Feldstein, J., Hicks, J., Benveniste, H., Speicher, M.R., Downing, J.R. and Lowe, S.W. (2014). PTEN action in leukemia dictated by the tissue microenvironment. Nature. doi:10.1038/nature13239
  • Rodriguez JP, Coulter M, Miotke J, Meyer RL, Takemaru K, Levine JM. (2014) Abrogation of ß-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury. Journal of Neuroscience 34(31):10285-97
  • Burke MC, Li FQ, Cyge B, Arashiro T, Brechbuhl HM, Chen X, Siller SS, Weiss MA, O'Connell CB, Love D, Westlake CJ, Reynolds SD, Kuriyama R, Takemaru K. (2014). Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation. J Cell Biol. Oct 13;207(1):123-37. doi: 10.1083/jcb.201406140. PMID: 25313408

2013

  • Adada M, Canals D, Hannun YA, Obeid LM, 2013, Sphingolipid regulation of ezrin, radixin, and moesin proteins family: Implications for cell dynamics, Biochim Biophys Acta, 1841(5):727-737
  • Adada M, Canals D, Hannun YA, Obeid LM, 2013, Sphingosine-1-phosphate receptor 2, FEBS J. 280:6354-66
  • Adada M, Orr-Gandy KA, Snider AJ, Canals D, Hannun YA, Obeid LM, Clarke CJ., 2013, Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor KB activation, J Biol Chem., 288(38):27667-79
  • Al-Shareffi E, Chaubard JL, Leonhard-Melief C, Wang SK, Wong CH, Haltiwanger RS, 2013, “6-Alkynyl Fucose is a Bioorthogonal Analog for O-Fucosylation of Epidermal Growth Factor-like Repeats and Thrombospondin Type-1 Repeats by Protein O-fucosyltransferases 1 and 2.” Glycobiology, 2013 Feb;23(2):188-98
  • Chang A*, Schiebel J*, Yu W, Bommineni GR, Pan P, Baxter MV, Khanna A, Sotriffer CA, Kisker C, Tonge PJ. Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex. Biochemistry. 2013 Jun 18;52(24):4217-28
  • Feinstein I. & Kritzer MF. (2013). Acute NMDA Receptor Hypofunction induced by MK801 Evokes Sex-Specific Changes in Behaviors Observed in Open Field Testing in Adult Male and Proestrus Female Rats. Neuroscience. 228:200-14.  PMID: 23085219.
  • Griffen TC, Wang L, Fontanini A and Maffei A (2013) “Developmental regulation of spatio-temporal patterns of cortical circuit activation.” Frontiers in Cellular Neuroscience. 6:65. PMID: 23316135
  • Guja KE, Venkataraman K, Yakubovskaya E, Shi H, Mejia E, Hambardjieva E, Karzai AW, Garcia-Diaz M. 2013. “Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1.” Nucleic Acids Res. 41(16):7947-59. PMID: 23804760
  • Hanel W, Marchenko N, Xu S, Xiaofeng Yu S, Weng W, Moll U. Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis. Cell Death Differ. 2013 Jul; 20(7):898-909 
  • Hu ZI, Kotarba AM, Van Nostrand WE. (2013). Absence of Nitric Oxide Synthase 3 Increases Amyloid β-Protein Pathology in Tg-5xFAD Mice. Neurosci Med. Jun;4(2):84-91. PMID: 24159423
  • Elizabeth Yakaboski*, Alexander Jares*, Yupo Ma MD PhD Hepatology. 2013, Stem cell gene SALL4 in aggressive hepatocellular carcinoma: A Cancer Stem cell-specific target?   [Epub ahead of print] *equal contribution
  • Kazi R, Gan Q, Talukder I, Markowitz M. Salussolia CL, Wollmuth LP. Asynchronous movements prior to pore opening in NMDA receptors. J Neurosci. 2013;33(29):12052-66. PMID: 23864691
  • Salussolia CL, Gan Q, Kazi R, Singh P, Allopenna J, Furukawa H, et al. A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors. J Neurosci. 2013;33(23):9840-5. PMID: 23739980
  • Kazi R, Gan Q, Talukder I, Markowitz M, Salussolia CL, Wollmuth LP. (2013). Asynchronous movements prior to pore opening in NMDA receptors. Neurosci. 2013 Jul 17;33(29):12052-66. doi: 10.1523/JNEUROSCI.5780-PMID: 2386469112.2013.
  • Salussolia CL, Gan Q, Kazi R, Singh P, Allopenna J, Furukawa H, Wollmuth LP. (2013). A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors.J Neurosci. Jun 5;33(23):9840-5. doi: 10.1523/JNEUROSCI.2626-12.2013. PMID: 23739980
  • Huang W#, Loganantharaj R#, Schroeder B#, Fargo D, Li L. (2013). PAVIS: a tool for Peak Annotation and Visualization. Bioinformatics. PMID: 24008416 (#: co-first-authors.)Siolas, D., and Hannon, G. J. (2013). Patient-derived tumor xenografts: transforming clinical samples into mouse models. Cancer research 73, 5315-5319
  • Kazi R, Gan Q, Talukder I, Markowitz M, Salussolia CL, Wollmuth LP.  (2013). Asynchronous movements prior to pore opening in NMDA receptors.  J Neurosci. 33(29):12052-66.  PIMD: 23864691

2012

  • Abraham A., Silverstein, D. Stellate Shaped Ulcers and Violaceous Plaques. Journal of the American Academy of Dermatology. Accepted 6/14/2012. 
  • Guja KE, Garcia-Diaz M. (2012). Hitting the brakes: termination of mitochondrial transcription.Biochim Biophys Acta. Sep-Oct;1819(9-10):939-47. doi: 10.1016/j.bbagrm.2011.11.004. Epub 2011 Nov 25. Review. PMID: 22137970
  • Hanel W, Moll UM. (2012). Links between mutant p53 and genomic instability. J Cell Biochem.113(2):433-9. doi: 10.1002/jcb.23400. Review. PMID:22006292
  • Wu C, Jares A, Winkler T, Xie J, Metais JY, Dunbar CE. (2012). High efficiency restriction enzyme free LAM-PCR approach for tracking lentiviral integration sites does not abrogate retrieval bias. Hum Gene Ther.*equal contribution PMID:22992116
  • *Schneider JG, Khalil DN. (2012). Why does Oncotype DX recurrence score reduce adjuvant chemotherapy use? Breast Cancer Res Treat. 134(3):1125-32. PMID: 22723033 
  • Levit NA, Mese G, Basaly MG, White TW. (2012). Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome. Biochim Biophys Acta. Aug;1818(8):2014-9. doi: 10.1016/j.bbamem.2011.09.003. Epub 2011 Sep 10. Review. PMID: 21933663
  • Salussolia CL, Wollmuth LP. (2012). Flip-flopping to the membrane. Neuron. 2012 Nov 8;76(3):463-5. doi: 10.1016/j.neuron.10.022. Erratum in: Neuron. 2012 Dec 20;76(6):1238. PMID: 23141057
  • *Schwartz NU, Zhong L, Bellemer A, Tracey WD. (2012). Egg laying decisions in Drosophila are consistent with foraging costs of larval progeny. PLoS One. 7:e37910
  • Interaction between Genetic Polymorphisms of Drug Metabolizing Enzymes and Lifestyle Factors in the Risk of Breast Cancer in a Sample of Lebanese Women *Sharma H, Alilain WJ, Sadhu A, Silver J. (2012). Treatments to restore respiratory function after spinal cord injury and their implications for regeneration, plasticity and adaptation. Exp Neurol. 235:18-25
  • *Siller SS, Broadie K. (2011). Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase. Dis Model Mech. 4:673-85
  • *Peters TM, et al. (on behalf of the InterAct Consortium). Validity of a short questionnaire to assess physical activity in 10 European countries. European Journal of Epidemiology. 2012 Jan; 27(1): 15-25 

2011

  • Bukhari N, Torres L, Robinson JK, Tsirka SE. (2011). Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system. J Neurosci. 31(42):14931-43. PMID: 22016526 
  • Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. (2011). A rapid and scalable system for studying gene function in mice using conditional RNA interference.Cell. 145(1):145-58. PMID:21458673
  • Cheney L, Hou JC, Morrison S, Pessin J, Steigbigel RT. (2011). Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection. J Infect Dis. 203(12):1824-31. PMID:21606541
  • *He P, Kramer K, Smith-Jones P, Zanzonico P, Humm J, Larson SM, Cheung NK. (2011). Two-compartment model of radioimmunotherapy delivered through cerebrospinal fluid. Eur J Nucl Med Mol Imaging. 38:334-42
  • Kazi R*, Talukder I*, Wollmuth LP. (2011). GluN1-specific redox effects on the kinetic mechanism of NMDA receptor activation. Biophysical Journal.* - equal contribution. 101(10):2389-98. PMID:22098737
  • Salussolia CL, Corrales A, Talukder I, Kazi R, Akgul, G, Bowen M, Wollmuth, LP. (2011). Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Journal of Biological Chemistry. 286(46):40205-18. PMID:21930708
  • *Goldstein JA, Kelly SM, LoPresti PP, Heydemann A, Earley JU, Ferguson EL, Wolf MJ, McNally EM. (2011). TGFb signaling drives progression in muscular dystrophy. Human Molecular Genetics 20; 20(5):894-904. PMID: 21138941
  • Lazarus MS, Huang ZJ. (2011). Distinct maturation profiles of perisomatic and dendritic targeting GABAergic interneurons in the mouse primary visual cortex during the critical period of ocular dominance plasticity. J Neurophysiol. 106(2):775-87. PMID:21613595
  • Salussolia CL, Corrales A, Talukder I, Kazi R, Akgul G, Bowen M, Wollmuth LP. (2011). Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. J Biol Chem. 286(46):40205-18. PMID:21930708Salussolia CL, Prodromou ML, Borker P, Wollmuth LP. (2011). Arrangement of subunits in functional NMDA receptors. J Neurosci. 31(31):11295-304. PMID:21813689
  • Seandel M, Rafii S. (2011). Reproductive biology: In vitro sperm maturation. Nature. 471(7339):453-5. No abstract available. PMID: 21430767*Faraj W, Sbaity E, Mukherji D, Shamseddine A, Shamseddine A, Khalife M. (2011). Successful one stage operation for a synchronous, duodenal carcinoma, colonic carcinoma and renal oncocytoma in an adult patient. World J Surg Oncol. 9:99
  • *Siller SS, Broadie K. (2012). Matrix metalloproteinases and minocycline: therapeutic avenues for fragile x syndrome. Neural Plast. 124548
  • Talukder I, Kazi R, Wollmuth LP. (2011). GluN1-specific redox effects on the kinetic mechanism of NMDA receptor activation. Biophys J. 101(10):2389-98. PMID:22098737
  • Salussolia CL, Corrales A, Talukder I, Kazi R, Akgul G, Bowen M, Wollmuth LP. (2011). Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. J Biol Chem. 286(46):40205-18. Epub 2011 Sep 19. PMID:21930708
  • Talukder I, Wollmuth LP. (2011). Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening. J Gen Physiol. 138(2):179-94. PMID:21746848
  • Yeku O, Frohman MA. (2011). Rapid amplification of cDNA ends (RACE). Methods Mol Biol. 703:107-22. PMID:21125486

2010

  • McGillick BE, Balius TE, Mukherjee S, Rizzo RC. (2010). Origins of resistance to the HIVgp41 viral entry inhibitor T20. Biochemistry. 49(17):3575-92. PMID:20230061
  • *Peters TM, Moore SC, Xiang YB, et al. Accelerometer-measured physical activity in Chinese adults. American Journal of Preventive Medicine. 2010 Jun; 38(6): 583-91
  • *Peters TM, Shu XO, Moore SC, et al. Validity of a physical activity questionnaire in Shanghai. Medicine and Science in Sports and Exercise. 2010 Dec; 42(12): 2222-30
  • Takiguchi M, James C, Josefsson EC, Carmichael CL, Premsrirut PK, Lowe SW, Hamilton JR, Huang DC, Kile BT, Dickins RA. Transgenic, inducible RNAi in megakaryocytes and platelets in mice. J Thromb Haemost. 2010 Dec;8(12):2751-6. PMID: 21138522
  • Gadow KD, Roohi J, DeVincent CJ, Kirsch S, Hatchwell E. (2010). Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. J Autism Dev Disord. 40(9):1139-45.PMID: 20155310
  • *Hobbs RM, Seandel M, Falciatori I, Rafii S, Pandolfi PP. (2010). Plzf regulates germline progenitor self-renewal by opposing mTORC1. Cell. 142(3):468-79. PMID: 20691905
  • *Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S. (2010). Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell. 6(3):251-64. PMID: 20207228
  • *James D, Nam HS, Seandel M, Nolan D, Janovitz T, Tomishima M, Studer L, Lee G, Lyden D, Benezra R, Zaninovic N, Rosenwaks Z, Rabbany SY, Rafii S. (2010). Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nat Biotechnol. 28(2):161-6. PMID: 20081865
  • *Faraj W, Mukherji D, El Majzoub N, Shamseddine A, Shamseddine A, Khalife M. (2010). Primary undifferentiated embryonal sarcoma of the liver mistaken for hydatid disease.World J Surg Oncol. 8:58. PMID: 20615265
  • Talukder I, Borker P, Wollmuth LP. (2010). Specific sites within the ligand-binding domain and ion channel linkers modulate NMDA receptor gating. J Neurosci. 30(35):11792-804. PMID:20810899
  • Hedbacker K, Birsoy K, Wysocki RW, Asilmaz E, Ahima RS, Farooqi IS, Friedman JM. (2010). Antidiabetic effects of IGFBP2, a leptin-regulated gene. Cell Metab. Jan.; 11(1):11-22.PMID:20074524
  • Dall'Armi C, Hurtado-Lorenzo A, Tian H, Morel E, Nezu A, Chan RB, Yu WH, Robinson KS,Yeku O, Small SA, Duff K, Frohman MA, Wenk MR, Yamamoto A, Di Paolo G. (2010). The phospholipase D1 pathway modulates macroautophagy. Nat Commun.1:142. doi: 10.1038/ncomms1144. PMID:21266992

2009

  • Hoos MD, Ahmed M, Smith SO, and Van Nostrand WE. (2009). Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in-vitro. Biochemistry. 48(22):4720-7Liao MC, Ahmed M, Smith SO, and Van Nostrand WE. (2009). Degradation of amyloid beta protein by purified myelin basic protein. J Biol Chem. 284(42):28917-25
  • Bale TA and Solomon IC. (2009). Influence of 5-HT2A receptor blockade on phrenic nerve discharge at three levels of extracellular K+ in arterially-perfused adult rat. Adv Exp Med Biol 669: 139-142
  • Entcheva E, Bien H. (2009). Mechanical and spatial determinants of cytoskeletal geodesic dome formation in cardiac fibroblasts. Integr Biol (Camb). 1(2):212-9. PMID: 20023805
  • *Johansson BE, Brett IC. (2009) Mouse models of influenza. Handbook on Immunosenescence: basic understanding and clinical applications. Fulop, T.; Franceschi, C.; Hirokawa, K.; Pawelec, G. (Eds.) Springer Science+Business Media BV. 
  • Ford B, Boykevisch S, Zhao C, Kunzelmann S, Bar-Sagi D, Herrmann C, Nassar N. (2009). Characterization of a Ras mutant with identical GDP- and GTP-bound structures .Biochemistry. 48(48):11449-57. PMID: 19883123
  • Marchenko, ND, Hanel W, Becker K, Reich N, and Moll UM. Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin alpha3 binding. EMBO.
  • Robak LA, Venkatesh K, Lee H, Raiker SJ, Duan Y, Lee-Osbourne J, Hofer T, Mage RG, Rader C, Giger RJ. (2009). Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition. J Neurosci. 29(18):5768-83. PMID: 19420245
  • *Lu MT, Cai T, Ersoy H, Whitmore AG, Levit NA, Goldhaber SZ, Rybicki FJ. (2009). Comparision of ECG gated versus non-gated CT ventricular measurements in thirty patients with acute pulmonary embolism. International Journal of Cardiovascular Imaging. Jan;25(1):101-7. Epub 2008 Jul 15
  • *Steigner ML, Otero HJ, Cai T, Mitsouras D, Nallamshetty L, Whitmore AG, Ersoy H, Levit NA, Di Carli MF, Rybicki FJ. (2009). Narrowing the phase window in prospectively ECG-gated single heart beat 320-detector row coronary angiography. International Journal of Cardiovascular Imaging. Jan;25(1):85-90. Epub 2008 Jul 29
  • *Newcomb, B. and A. Bedalov. (2009). Identification of inhibitors of chromatin modifying enzymes using the yeast phenotypic screens. Methods Mol Biol. 548: p. 145-60
  • *Moore SC, Peters TM, Ahn J, et al. Age-specific physical activity and prostate cancer risk among white men and black men. Cancer. 2009 Nov; 115(21): 5060-70
  • *Peters TM, Moore SC, Gierach GL, et al. Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP Diet and Health Study. BMC Cancer. 2009 Oct; 9(1): 349
  • *Peters TM, A Schatzkin, GL Gierach, SC Moore, JV Lacey Jr, NJ Wareham, U Ekelund, AR Hollenbeck, MF Leitzmann. Physical activity and postmenopausal breast cancer risk in the NIH-AARP Diet and Health study. CEBP 18(1):289-96, 2009
  • Gadow KD, Roohi J, DeVincent CJ, Kirsch S, Hatchwell E. (2009). Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder. J Autism Dev Disord. 39(11):1542-51. PMID: 19582565
  • Hajcak G, Castille C, Olvet DM, Dunning JP, Roohi J, Hatchwell E. (2009). Genetic variation in brain-derived neurotrophic factor and human fear conditioning. Genes Brain Behav. 8(1):80-5. PMID: 19220486
  • Roohi J, DeVincent CJ, Hatchwell E, Gadow KD. (2009). Association of a monoamine oxidase-a gene promoter polymorphism with ADHD and anxiety in boys with autism spectrum disorder. J Autism Dev Disord. 39(1):67-74. PMID: 18566880
  • Roohi J, Montagna C, Tegay DH, Palmer LE, DeVincent C, Pomeroy JC, Christian SL, Nowak N, Hatchwell E. (2009). Disruption of contactin 4 in three subjects with autism spectrum disorder. J Med Genet. 46(3):176-82. PMID: 18349135
  • Potapova, I.A., Doronin, S.V., Kelly, D.J., Rosen, A.B., Schuldt, A.J.T., Lu, Z., Kochupura, P.V., Robinson, R.B., Rosen, M.R., Brink, P.R., Gaudette, G.R., and Cohen, I.S. (2009)  Enhanced recovery of mechanical function in the canine heart by seeding an extracellular matrix patch with mesenchymal stem cells committed to a cardiac lineage.  Amer. J. Physiology.  295:H2257-63 
  • Kelly DJ, Rosen AB, Schuldt AJ, Kochupura PV, Doronin SV, Potapova IA, Azeloglu EU, Badylak SF, Brink PR, Cohen IS, Gaudette GR. (2009) Increased myocyte content and mechanical function within a tissue-engineered myocardial patch following implantation. Tissue Eng Part A. 15(8):2189-201
  • Kelly DJ, Rosen AB, Schuldt AJ, Kochupura PV, Doronin SV, Potapova IA, Azeloglu EU, Badlyak SF, Brink PR, Cohen IS, Gaudette GR. (2009). Increased Myocyte Content and Mechanical Function Within a Tissue-Engineered Myocardial Patch Following Implantation.Tissue Eng Part A. Ahead of print. PMID: 19231971
  • *Hatoum HA, Jamali FR, El-Saghir NS, Musallam KM, Seoud M, Dimassi H, Abbas J, Khalife M, Boulos FI, Tawil AN, Geara FB, Salem Z, Shamseddine AA, Al-Feghali K,Shamseddine AI. (2009). Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positive breast cancer. Ann Surg Oncol. 16(12):3388-95
  • *Tucciarone J, Chuang KH, Dodd SJ, Silva A, Pelled G, Koretsky AP. (2009). Layer Specific Tracing of Cortical and Thalamic Connections Using Manganese Enhanced MRI.Neuroimage. Feb 1; 44(3):923-31. PMID: 18755280
  • Yeku O, Scotto-Lavino E, Frohman MA. (2009). Identification of Alternative Transcripts Using Rapid Amplification of cDNA Ends (RACE). Methods Mol Biol. 590:279-94. PMID: 19763511
  • Su W, Yeku O, Olepu S, Genna A, Park JS, Ren H, Du G, Gelb MH, Morris AJ, Frohman MA. (2009). 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol Pharmacol. 75(3):437-46. PMID: 19064628
  • Zanazzi, George, Matthews, G. (2009). The molecular architecture of ribbon presynaptic terminals. Molecular Neurobiology. 39:130-48. PMID: 19253034

2008

  • *Murphy SL, Bhagwat A, Edmonson S, Zhou S, High KA. (2008). High-throughput screening and biophysical interrogation of hepatotropic AAV. Mol Ther. 16(12):1960-7. PMID:18827805
  • Jia Z, Bien H, Entcheva E. (2008). A sensitive algorithm for automatic detection of space-time alternating signals in cardiac tissue. Conf Proc IEEE Eng Med Biol Soc. 153-6. PMID: 19162616
  • *Johansson BE, Brett IC. (2008). Recombinant influenza B virus HA and NA antigens administered in equivalent amounts are immunogenically equivalent and induce equivalent homotypic and broader heterovariant protection in mice than conventional and live influenza vaccines. Human Vaccine. 4(6):420-4
  • *Mohiyiddeen G, Brett I, Jude E. (2008). Infective endocarditis caused by Staphylococcus aureus in a patient with atopic dermatitis: a case report. J Med Case Rep. 2:143. PMID:18454875
  • Nolin W, Emmetsberger J, Bukhari N, Zhang Y, Levine J, Tsirka S. (2008). tPA-Mediated Generation of Plasmin is Catalyzed by the Proteoglycan NG2. GLIA. 56:177-189. PMID: 18000864
  • Zhou CC , Chen KY , Breslow JL. (2008). Activation of pregnane X receptor induces hypercholesterolemia and accelerates atherosclerosis in mice. ATVB. Jun; 28(6):E32
  • *Lokshina I, Feinstein I, Agin C, Katz R. (2008). Diagnosis and treatment of glossopharyngeal and vagal neuropathies in a patient with laryngopharyngeal reflux. Anesthesiology. 109(4):741-3. No abstract available. PMID:18813053
  • *Anderson, B. J., Larkin, C., Guja, K., and Schildbach, J. F. Using fluorophore-labeled oligonucleotides to measure affinities of protein-DNA interactions. Methods in Enzymology. 2008, 450:253-272
  • *Hekman, K., Guja, K., Larkin, C., and Schildbach, J. F. An intrastrand three-DNA-base interaction is a key specificity determinant of F transfer initiation and of F TraI relaxase DNA recognition and cleavage. Nucleic Acids Research. 2008, 36(14):4565-4572
  • *Lai, L., Leone, T. C., Zechner, C., Schaeffer, P. J., Kelly, S. M., Flanagan, D. P., Medeiros, D. M., Kovacs, A., and Kelly, D. P. (2008) Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart, Genes Dev22, 1948-1961
  • Kwofie MA, Skowronski J. (2008). Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors. J Biol Chem. 283(6):3088-96. PMID: 18056264
  • Mittra E, Rubin C, Gruber B, Qin YX. (2008). Evaluation of trabecular mechanical and microstructural properties in human calcaneal bone of advanced age using mechanical testing, microCT, and DXA. J Biomech. 41(2):368-75. PMID: 17953972
  • *Peters TM, Ekelund U, Leitzmann MF, et al. Physical activity and mammographic breast density in the EPIC-Norfolk Cohort Study. American Journal of Epidemiology. 2008 Mar; 167(5): 579-585.
  • *Moore SC, TM Peters, J Ahn, Y Park, A Schatzkin, D Albanes, R Ballard-Barbash, A Hollenbeck, MF Leitzmann. (2008). Physical activity in relation to total, advanced, and fatal prostate cancer. CEBP. 17(9):2458-66
  • *Leitzmann MF, SC Moore, TM Peters, JV Lacey Jr, A Schatzkin, C Schairer, LA Brinton, D Albanes. (2008). Prospective study of physical activity and risk of postmenopausal breast cancer. Cancer Res. 10(5):R92
  • Gadow KD, Roohi J, DeVincent CJ, Hatchwell E. (2008). Association of ADHD, tics, and anxiety with dopamine transporter (DAT1) genotype in autism spectrum disorder. J Child Psychol Psychiatry. 49(12):1331-8. PMID: 19120712
  • Gao Z, Wang J, Thiex R, Rogove AD, Heppner FL, Tsirka SE. (2008). Microglial activation and intracerebral hemorrhage. Acta Neurochir Suppl. 105:51-3. PMID: 19066082
  • Roohi J, Cammer M, Montagna C, Hatchwell E. (2008). An improved method for generating BAC DNA suitable for FISH. Cytogenet Genome Res. 121(1):7-9. PMID: 18544919
  • Roohi J, Tegay DH, Pomeroy JC, Burkett S, Stone G, Stanyon R, Hatchwell E. (2008). A de novo apparently balanced translocation [46,XY,t(2;9)(p13;p24)] interrupting RAB11FIP5 identifies a potential candidate gene for autism spectrum disorder. Am J Med Genet B Neuropsychiatr Genet. 147B(4):411-7. PMID: 18384058
  • Rosen, M.R., Brink, P.R., Cohen, I.S., Danilo Jr., P., Robinson, R.B., Rosen, A.B., and Szabolcs, M.J. (2008). Regenerative therapies in electrophysiology and pacing. Journal of Interventional Cardiac Electrophysiology. 22(2):87-98. PMID: 18363088
  • Potapova, I.A., Doronin, S.V., Kelly, D.J., Rosen, A.B., Schuldt, A.J.T., Lu, Z., Kochupura, P.V., Robinson, R.B., Rosen, M.R., Brink, P.R., Gaudette, G.R., and Cohen, I.S. Enhanced recovery of mechanical function in the canine heart by seeding an extracellular matrix patch with mesenchymal stem cells committed to a cardiac lineage. American Journal of Physiology. Provisional acceptance.
  • Zhan L, Rosenberg A, Bergami KC, Yu M, Xuan Z, Jaffe AB, Allred C, Muthuswamy SK. (2008). Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell. 135(5):865-78. PMID: 19041750
  • *Geer CB, Stasko NA, Rus IA, Lord ST, Schoenfisch MH. Influence of glutathione and its derivatives on fibrin polymerization. Biomacromolecules. 2008 Jul;9(7):1876-82
  • Potapova IA, Doronin SV, Kelly DJ, Rosen AB, Schuldt AJ, Lu Z, Kochupura PV, Robinson RB, Rosen MR, Brink PR, Gaudette GR, Cohen IS. (2008). Enhanced recovery of mechanical function in the canine heart by seeding an extracellular matrix patch with mesenchymal stem cells committed to a cardiac lineage. Am J Physiol Heart Circ Physiol. 295(6):H2257-63. PMID: 18835924
  • Schuldt AJ, Rosen MR, Gaudette GR, Cohen IS. Repairing damaged myocardium: evaluating cells used for cardiac regeneration. (2008). Curr Treat Options Cardiovasc Med. 10(1):59-72. PMID: 18325308
  • *Seandel M, Butler JM, Kobayashi H, Hooper AT, White IA, Zhang F, Vertes EL, Kobayashi M, Zhang Y, Shmelkov SV, Hackett NR, Rabbany S, Boyer JL, Rafii S. (2008). Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proc Natl Acad Sci U S A. 105(49):19288-93. PMID: 19036927
  • *Kim J, Seandel M, Falciatori I, Wen D, Rafii S. (2008). CD34+ testicular stromal cells support long-term expansion of embryonic and adult stem and progenitor cells. Stem Cells. 26(10):2516-22. PMID: 18669907
  • *Seandel M, Butler J, Lyden D, Rafii S. (2008). A catalytic role for proangiogenic marrow-derived cells in tumor neovascularization. Cancer Cell. 13(3):181-3. PMID: 18328420
  • *Seandel M, Falciatori I, Shmelkov SV, Kim J, James D, Rafii S. (2008). Niche players: spermatogonial progenitors marked by GPR125. Cell Cycle. 7(2):135-40. PMID: 18256534
  • *Silva A, Lee JH, Wu WH, Tucciarone J, Aoki I, Koretsky AP. Cortical Laminar Architecture Detected Non-Invasively Using Manganese Enhanced MRI. Journal of Neuroscience Methods. 2008. 167(2): 246-257. PMID: 17936913
  • Teressa G, Prives J. (2008). Cell culture-based analysis of postsynaptic membrane assembly in muscle cells. Biol Proced Online. 10:58-65. PMID: 19461953

2007

  • Hoos MD, Ahmed M, Smith SO, and Van Nostrand WE. (2007). Inhibition of familial cerebral amyloid angiopathy mutant amyloid beta-protein fibril assembly by myelin basic protein.Journal of Biological Chemistry. 282(13):9952-61
  • *Niranjanakumari N, Day-Storms JJ, Ahmed M, Hsieh J, Zahler NH, Venters RA, and Fierke CA. (2007). Probing the architecture of the b. subtilis RNase P holoenzyme active site by crosslinking and affinity cleavage. RNA. 13(4):521-35
  • Bhatt, DH, McLean, DL, Hale, ME, Fetcho, JR. (2007). Grading movement strength by changes in firing intensity versus recruitment of spinal interneurons. Neuron. 53(1):91-102. PMID: 17196533
  • Bien H, Parikh P and Entcheva E (2007). Lenses and effective spatial resolution in macroscopic optical mapping. Physics in Medicine and Biology. 52(4):941-960. PMID:17264363
  • Chung CY, Bien H, Entcheva E. (2007). J Cardiovasc Electrophysiol. 18(12):1323-9. PMID: 17916158
  • *Johansson BE, Brett IC. (2007). Changing perspective on immunization against influenza.Vaccine. 25(16):3062-5
  • Wolfrum S , Teupser D , Tan M , Chen KY, Breslow JL. (2007). The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappa B target genes. PNAS. Nov. 20; 104(47):18601-18606. PMCID 2141823
  • Cello, J., Toyoda, H., De Jesus, N., Dobrikova, E. Y., Gromeier, M., and Wimmer, E. (2007). Growth phenotypes and biosafety profiles in poliovirus-receptor transgenic mice of recombinant oncolytic polio/human rhinoviruses. J Med Virol. 80(2):352-9. PMID: 18098139
  • De Jesus, N. H. (2007). Epidemics to eradication: the modern history of poliomyelitis. Virol J. 4:70-88
  • DiMartino SJ, Trujillo G, McVoy LA, Zhang J, Kew RR. (2007). Upregulation of vitamin D binding protein (Gc-globulin) binding sites during neutrophil activation from a latent reservoir in azurophil granules. Mol Immunol. 44(9):2370-7. PMID: 17113648
  • Benveniste H, Ma Y, Dhawan J, Gifford A, Smith SD, Feinstein I, Du C, Grant SC, Hof PR. (2007). Anatomical and functional phenotyping of mice models of Alzheimer's disease by MR microscopy. Ann N Y Acad Sci. 1097:12-29. Review. PMID:17413006
  • Mikhailik A, Ford B, Keller J, Chen Y, Nassar N, Carpino N. (2007). A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling. Mol Cell. 27(3):486-97. PMID: 17679096
  • Maitra A., Shen F., Hanel W., Mossman K., Tocker J., Swart D., Gaffen SL. (2007). Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression. Proc Natl Acad Sci. U.S.A. 104(18):7506-11. PMID: 17456598
  • Tanner MJ., Hanel W., Gaffen SL., Lin X. (2007). CARMA1 coiled-coil domain is involved in the oligomerization and subcellular localization of CARMA1 and is required for T-cell receptor-induced NF-kappaB activation. J Biol Chem. 282(23):17141-7. PMID: 17428801
  • Kramer JM., Hanel W., Shen F., Isik N., Malone J.P., Maitra A., Sigurdson W., Swart D., Tocker J., Jin T., Gaffen SL. (2007). Cutting Edge: Identification of a Pre-Ligand Assembly Domain (PLAD) and Ligand Binding Site in the IL-17 Receptor. J Immunology. 179(10): 6379:83. PMID: 17982023
  • Allikian, M. J., Bhabha, G., Dospoy, P., Heydemann, A., Ryder, P., Earley, J. U., Wolf, M. J., Rockman, H. A., and McNally, E. M. (2007) Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants, Hum Mol Genet 16, 2933-2943. (Follow up paper in press Goldstein, JA and Kelly, SM)
  • Manganas LN, Zhang X, Li Y, Hazel RD, Smith SD, Wagshul ME, Henn F, Benveniste H, Djuric PM, Enikolopov G, Maletic-Savatic M. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science. 2007. 318(5852):980-5
  • DiMartino SJ, Trujillo G, McVoy LA, Zhang J, Kew RR. (2007). Upregulation of vitamin D binding protein (Gc-globulin) binding sites during neutrophil activation from a latent reservoir in azurophil granules. Mol Immunol. 44(9):2370-7. PMID: 17113648
  • *Thaminy, S., Newcomb, B., Kim, J., Gatbonton, T., Foss, E., Simon, J., Bedalov, A. (2007). Hst3 is regulated by Mec1-dependent proteolysis and controls the S phase checkpoint and sister chromatid cohesion by deacetylating histone H3 at lysine 56. J Biol Chem. 282(52): p. 37805-14
  • Peters TM, U Ekelund, MF Leitzmann, D Easton, R Warren, R Luben, S Bingham, KT Khaw, NJ Wareham. (2007). Physical Activity and Mammographic Breast Density in the EPIC-Norfolk Cohort Study. American Journal of Epidemiology. 167(5):579-585
  • Dickins, R.A., McJunkin, K., Hernando, E., Premsrirut, P.K., Krizhanovsky, V., Burgess, D.J., Kim, S.Y., Cordon-Cardo, C., Zender, L., Hannon, G.J. and Lowe, S.W. (2007). Tissue-specific and reversible RNAi in transgenic mice. Nature Genetics. 39:914-921
  • Rampal R, Luther KB, Haltiwanger RS. (2007). Notch signaling in normal and disease States: possible therapies related to glycosylation. Curr Mol Med. 7(4):427-45. PMID: 17584081
  • Sheehan JJ, Zhou C, Gravanis I, Rogove AD, Wu YP, Bogenhagen DF, Tsirka SE. (2007). Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. J Neurosci. 27(7):1738-45. PMID: 17301181
  • Tegay DH, Lane AH, Roohi J, Hatchwell E. (2007). Contiguous gene deletion involving L1CAM and AVPR2 causes X-linked hydrocephalus with nephrogenic diabetes insipidus. Am J Med Genet A. 143(6):594-8. PMID: 17318848
  • Cohen, I.S., Rosen, A.B., and Gaudette G.R. (2007). A Caveat Emptor for myocardial regeneration: Mechanical without electrical recovery will not suffice. Journal of Molecular and Cellular Cardiology. 42(2): 285-288
  • Rosen, A.B. (2007). Everything is illuminated … with quantum dots. Nanomedicine. 2(6):51-954
  • Rosen, A.B., Kelly, D.J., Schuldt, A.J.T., Lu, J., Potapova, I.A., Doronin, S.V., Robichaud, K.J., Robinson, R.B., Rosen, M.R., Brink, P.B., Gaudette, G.R., and Cohen, I.S. (2007). Finding Fluorescent Needles in the Cardiac Haystack: Tracking human mesenchymal stem cells loaded with quantum dots for quantitative in vivo 3-D fluorescence analysis. Stem Cells. 25(8):2128 -2138
  • Potapova, I.A., Doronin, S.V., Kelly, D.J., Rosen, A.B., Schuldt, A.J.T., Lu, Z., Guo, Y., Kochupura, P.V., Robinson, R.B., Rosen, M.R., Brink, P.R., Gaudette, G.R., and Cohen, I.S. (2007). Replacing damaged myocardium. Journal of Electrocardiology. 40(6):S199-S201
  • Plotnikov, A.N., Shlapakova, I., Szabolcs, M.J., Danilo, Jr, P., Lorell, B.H., Potapova, I.A., Lu, Z., Rosen, A.B., Mathias, R.T., Brink, P.R., Robinson, R.B., Cohen, I.S., and Rosen, M.R. (2007). Xenografted adult human mesenchymal stem cells provide a platform for sustained biological pacemaker function in canine heart. Circulation. 116:706-713
  • *Geer CB, Rus IA, Lord ST, Schoenfisch MH. Surface-dependent fibrinopeptide A accessibility to thrombin. Acta Biomater. 2007 Sep;3(5):663-8
  • Salussolia, CL, Nalwalk JW, and Hough LB. (2007). Improgan-induced hypothermia: A role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature. Brain Research. 1152: 42-48
  • Potapova IA, Doronin SV, Kelly DJ, Rosen AB, Schuldt AJ, Lu Z, Guo Y, Kochupura PV, Robinson RB, Rosen MR, Brink PR, Gaudette GR, Cohen IS. (2007). Replacing damaged myocardium. J Electrocardiol. 40(6 Suppl):S199-201. PMID: 17993323
  • Rosen AB, Kelly DJ, Schuldt AJ, Lu J, Potapova IA, Doronin SV, Robichaud KJ, Robinson RB, Rosen MR, Brink PR, Gaudette GR, Cohen IS. (2007). Finding fluorescent needles in the cardiac haystack: tracking human mesenchymal stem cells labeled with quantum dots for quantitative in vivo three-dimensional fluorescence analysis. Stem Cells. 25(8):2128-38. PMID: 17495112
  • Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S. (2007). Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature. 449:346-50. PMID: 17882221.
  • Weston CA, Teressa G, Weeks BS, Prives J. (2007). Agrin and laminin induce acetylcholine receptor clustering by convergent, Rho GTPase-dependent signaling pathways. J Cell Sci. 120(Pt 5):868-75. PMID: 17298982
  • Zanazzi, George, Matthews, G. (2007). A doubleheader in endocytosis. Neuron. 56:939-42. PMID: 18093515

2006

  • Mastrangelo, I.A., Ahmed M., Sato T., Liu W., Wang C., Hough P. and Smith S.O. (2006). High Resolution Atomic Force Microscopy of soluble Abeta42 oligomers. Journal of Molecular Biology. 21:358:106-19
  • Sato T, Kienlen-Campard P, Ahmed M, Liu W, Li H, Elliott JI, Aimoto S, Constantinescu SN, Octave JN, and Smith SO (2006). Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42. Biochemistry. 45:5503-16
  • Archer H, Jura N, Keller J, Jacobson M, Bar-Sagi D. (2006). A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology. 131(6):1844-55. PMID: 17087933
  • Pogoda, HM, Sternheim, N, Bhatt, DH, Fetcho, JR, Talbot, WS. (2006). A genetic screen identifies genes essential for axon myelination in zebrafish. Developmental Biology. 298(1):118-31. PMID: 16875686
  • Singh R, Bien H, Entcheva E, Fenton FF. (2006). Inherent dispersion in restitution properties over space. Conf Proc IEEE Eng Med Biol Soc. 1:3935-8. PMID: 17947060
  • Shah U, Bien H, Entcheva E. (2006). Cardiac arrhythmogenesis and temperature. Conf Proc IEEE Eng Med Biol Soc. 1:841-4. PMID: 17946861Bien H, Entcheva E, Pertsov A, Mironov S, Vetter F (2006). Spatial frequency content in optical mapping of cardiac cell monolayers. Am J Physiol – Heart & Circ Physiol.291(3):H484-5. PMID: 16714358Bien H, Yin L and Entcheva E (2006). Calcium instabilities in mammalian cardiomyocyte networks. Biophysical Journal. 90(7):2628-40. PMID: 16399841
  • Entcheva E and Bien H (2006). Macroscopic optical mapping of excitation in cardiac cell networks with ultra-high spatiotemporal resolution. Progress in Biophysics and Molecular Biology. 92(2):232-57. PMID: 16330086
  • *Brett IC, Johansson BE. (2006). Variation of divalent cation requirements of influenza A virus N1 neuraminidases. J Biochem. 136:439-447*Johansson BE, Brett IC. (2006). An inactivated subvirion influenza A (H5N1) vaccine. NEJM. 354(25):2724-5. (Letter to the editor)
  • Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, Reich NC. (2006). Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection.J Immunol. 176(12):7462-70. PMID:16751392
  • Shah, A.B., DiMartino, S.J., Trujillo, G., and Kew, R.R. (2006). Selective inhibition of the C5a chemotactic cofactor function of the vitamin D binding protein by 1,25(OH)2 vitamin D3. Mol. Immunol. 43:1109-15. PMID: 16115686
  • Ford, B., Hornak, V., Kleinman, H., and Nassar , N. (2006). Structure of a transient intermediate for GTP hydrolysis by ras. Structure. 14:427-36. PMID: 16531227
  • Kleinman, H., Ford, B., Keller, J., Carpino, N., and Nassar, N. (2006). Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.Acta Crystallograph Sect F Struct. Biol. Cryst Commun. 62:218-20. PMID: 16511305
  • Golebiewska U, Gambhir A, Hangyás-Mihályné G, Zaitseva I, Rädler J, McLaughlin S. (2006). Membrane-bound basic peptides sequester multivalent (PIP2), but not monovalent (PS), acidic lipids. Biophys J. 91(2):588-99. PMID: 16648167
  • Boehm*, J., Ehrlich*, I., Hsieh*, H., Malinow, M. (2006). Two mutations preventing PDZ-protein interactions of GluR1 have opposite effects on synaptic plasticity. *Contributed equally to this work. Learn Mem. 13(5):562-5. PMID: 16980545
  • Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, Malinow R. (2006). AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron. 52(5):831-43. PMID: 17145504
  • Kassem, I.S. and Evinger, C. (2006). Asymmetry of blinking. Invest. Ophthalmol. Vis. Sci. 47:195-201. PMID: 16384962
  • LaLonde M, Janssens H, Yun S, Crosby J, Redina O, Olive V, Altshuller YM, Choi SY, Du G, Gergen JP, Frohman MA. (2006). A role for Phospholipase D in Drosophila embryonic cellularization. BMC Dev Biol. 6:60. PMID: 17156430
  • Rial Verde EM, Lee-Osbourne J, Worley PF, Malinow R, Cline HT. (2006). Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. Neuron. 52(3):461-74. PMID: 17088212
  • Lin, W., Mittra, E., and Qin, Y.X. (2006). Determination of ultrasound phase velocity in trabecular bone using time dependent phase tracking technique. J. Biomech Eng. 128:24-9
  • Mittra, E., S. Akella, and Y-X Qin (2006). The effects of embedding material, loading rate and magnitude, and penetration depth in nanoindentation of trabecular bone. Journal of Biomedical Materials Research A. 79:86-93. PMID: 16758456
  • *Lipska B, Peters T, Hyde TM, et al. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Human Molecular Genetics. 2006 Apr; 15(8): 1245-1258
  • Loriol C, Dupuy F, Rampal R, Dlugosz MA, Haltiwanger RS, Maftah A (2006). Germot A. Molecular evolution of protein O-fucosyltransferase genes and splice variants. Glycobiology. 6(8):736-47. PMID: 16679357
  • Herbert MR, Russo JP, Yang S, Roohi J, Blaxill M, Kahler SG, Cremer L, Hatchwell E (2006). Autism and environmental genomics. Neurotoxicology. 5:671-84. PMID: 16644012
  • Aranda V, Haire T, Nolan ME, Calarco JP, Rosenberg AZ, Fawcett JP, Pawson T, Muthuswamy SK. (2006). Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol. 8(11):1235-45. PMID: 17060907
  • Seandel M, Shia J, Linkov I, Maki RG, Antonescu CR, Dupont J. (2006). The activity of sunitinib against gastrointestinal stromal tumor seems to be distinct from its antiangiogenic effects. Clin Cancer Res. 12:6203-4 
  • Zijlstra, A., Seandel, M., Kupriyanova, T.A., Partridge, J.J., Madsen, M.A., Hahn-Dantona, E.A., Quigley, J.P., and Deryugina, E.I. (2006). Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells. Blood. 107:317-27
  • Koticha, D., Maurel, P., Zanazzi, G., Kane-Goldsmith, N., Basak, S., Babiarz, J., Salzer, J., Grumet, M. (2006). Neurofascin interactions play a critical role in clustering sodium channels, ankyrin G and beta IV spectrin at peripheral nodes of Ranvier. Devel. Biol. 293:1-12

2005

  • Jura, N., Archer, H., and Bar-Sagi, D. (2005). Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between. Cell Res. 15(1):72-7. PMID: 15686632
  • Zong X, Bien H, Chung CY, Yin L, Fang D, Chu B, Hsiao BS, and Entcheva E (2005). Electrospun fine-textured scaffolds for heart tissue constructs. Biomaterials. 26(26):5330-5338. PMID: 15814131
  • Entcheva E and Bien H (2005). Acoustic micromachining of three-dimensional surfaces for biological applications. Lab on a Chip. 5(2): 179-83. PMID: 15672132*Muddu BN, Umaar R, Kim WY, Zenios M, Brett I, Sharma Y. (2005). Whiplash injury of the shoulder: is it a distinct clinical entity? Acta Orthop Belg. 71(4):385-7. PMID:16184990
  • *Brett IC, Johansson BE. (2005). Immunization against Influenza A virus: Comparison of conventional inactivated, live-attenuated, and recombinant baculovirus produced purified hemagglutinin and neuraminidase vaccines in a murine model system. Virology. 339(2):273-80
  • *Noy A, Yahalom J, Zaretsky L, Brett I, Zelenetz AD. (2005). Gastric mucosa-associated lymphoid tissue detected by clonotypic polymerase chain reaction despite continuous pathologic remission induced by involved-field radiotherapy. J Clin Oncol. 23(16):3768-72
  • Windler-Hart SL, Chen KY, Chenn A. (2005). A cell behavior screen: identification, sorting, and enrichment of cells based on motility. BMC Cell Biol. 6:14DeJesus, N., Franco, D., Paul, A., Wimmer, E., and Cello, J. (2005). Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence. J. Virol. 79:14235-43
  • Mueller, S., Jiang, P., Reider, E., De Jesus, N., Iwasaki, A., Paul, A., Cello, J., and E. Wimmer. (2005). Pathogenesis and prevention of poliomyelitis and the chemical synthesis of poliovirus. Nova Acta Leopoldina NF 92, Nr. 344. 1-9
  • Ford, B., Skowronek, K., Boykevisch, S., Bar-Sagi, D., and Nassar, N. (2005). Structure of the G60A mutant of Ras: implications for the dominant negative effect. J. Biol Chem. 280:25697-705. PMID: 15878843
  • Hill, B.T. and Skowronski, J. (2005). Human N-myristoyltransferases form stable complexes with lentiviral nef and other viral and cellular substrate proteins. Journal of virology. 79(2): 1133-1141. PMID: 15613341
  • Evinger, C. and Kassem, I.S. (2005). Animal models of benign essential blepharospasm and hemifacial spasm. Animal Models of Movement Disorders (M LeDoux, Ed). Academic Press/Elsevier
  • Helfman, D.M., Kim, E.J., Lukanidin, E., and Grigorian, M. (2005). The metastasis associated protein S100A4: role in tumor progression and metastasis. Br. J. Cancer. 92:1955-8. PMID: 15900299
  • LaLonde, M.M., Janssens, H., Rosenbaum, E., Choi, S.-Y., Gergen, J.P., Colley, N.J., Stark, W.S., and Frohman, M.A. (2005). Regulation of Phototransduction Responsiveness and Retinal Degeneration by a Phospholipase D-generated Signaling Lipid. J. Cell Biol. 169:471-9
  • McVoy, L.A., and R.R. Kew. (2005). CD44 and annexin A2 mediate the C5a chemotactic cofactor function of the vitamin D binding protein. J. Immunol. 175:4754-60. PMID: 16177123
  • Mittra, E., Rubin, C., and Qin, Y.X. (2005). Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone. J. Biomech. 38:1229-37. PMID: 15863107
  • Rampal, R., Li, A.S., Moloney, D.J., Georgiou, S.A., Luther, K.B., Nita-Lazar. A., and Haltiwanger, R.S. (2005). Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats. J. Biol Chem. 280:42454-63. PMID: 16221665
  • Rampal, R., Arboleda-Velasquez, J.F., Nita-Lazar, A., Kosik, K.S., and Haltiwanger, R.S. (2005). Highly conserved O-fucose sites have distinct effects on Notch1 function. J. Biol Chem. 280:32133-40. PMID: 15994302
  • Arboleda-Velasquez, J.F., Rampal, R., Fung, E., Darland, D.C., Liu, M., Martinez, M.C., Donahue, C.P., Navarro-Gonzalez, M.F., Libby, P., D'Amore, P.A., Aikawa, M., Haltiwanger, R.S., and Kosik, K.S. (2005). CADASIL mutations impair Notch3 glycosylation by Fringe.Hum. Mol. Genet. 14:1631-9. PMID: 15857853
  • Saxena, A., Ma, B., Schramm, L., and Hernandez, N. (2005). Structure-function analysis of the human TFIIB-related factor II protein reveals an essential role for the C-terminal domain in RNA polymerase III transcription. Mol. Cell. Biol. 25:9406-18. PMID: 16227591
  • Silva, J.M., Li, M.Z., Chang, K., Ge, W., Golding, M.C., Rickles, R.J., Siolas, D., Hu, G., Paddison, P.J., Schlabach, M.R., Sheth, N., Bradshaw, J., Burchard, J., Kulkarni, A., Cavet, G., Sachdanandam, R., McCombie, W.R., Cleary, M.A., Elledge, S.J., and Hannon, G.J. (2005). Second-generation shRNA libraries covering the mouse and human genomes. Nat. Genet. 37:1281-8. PMID: 16200065
  • Siolas, D., Lerner, C., Burchard, J., Ge, W., Linsley, P.S., Paddison, P.J., Hannon, G.J., and Cleary, M.A. (2005). Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 23:227-31. PMID: 15619616
  • Melendez-Vasquez, C., Carey, D.J., Zanazzi, G., Reizes, O., Maurel P., and Salzer, J.L. (2005). Differential expression of proteoglycans at central and peripheral nodes of Ranvier.Glia. 52:301-308
  • Taveggia C., Zanazzi, G., Petrylak, A., Yano, H., Rosenbluth, J., Einheber, S., Xu, X., Esper, R., Loeb, J., Shrager, P., Falls, D.L., Chao, M.V., Role, L., and Salzer, J.L. (2005). Type III neuregulin-1 levels determine the ensheathment fate of axons. Neuron. 47:681-694

2004

  • Auster, A.S. and Joshua-Tor, L. (2004). The DNA-binding Domain of Human Papillomavirus Type 18 E1: Crystal Structure, Dimerization, and DNA Binding. Journal of Biological Chemistry. 279:3733-42. PMID: 14593106
  • Bhatt, D.H., Otto, S.J., Depoister, B., and Fetcho, J.R. (2004). Cyclic AMP-induced repair of zebrafish spinal circuits. Science. 305:254-8. PMID: 15247482
  • Fetcho, JR & Bhatt, DH (2004). Genes and photons: new avenues into the neuronal basis of behavior. Current Opinion in Neurobiology. 146:707-714. PMID: 15582372
  • Yin L, Bien H and Entcheva E (2004). Scaffold topography alters calcium handling in cultured cardiomyocyte networks. Am J Physiol – Heart & Circ Physiol. 287(3): H1276-H1285. PMID: 15105172
  • Entcheva E, Bien H, Yin L, Chung C-Y, Farrell M and Kostov Y (2004). Functional cardiac cell constructs on cellulose-based scaffolding. Biomaterials. 25(26):5753-5762. PMID: 15147821
  • *Kilbourne ED, Pokorny BA, Johansson B, Brett I, Milev Y, Matthews JT. (2004). Protection of mice with recombinant influenza virus neuraminidase. J Infect Dis. 189(3):459-61 
  • Olszewski RT, Bukhari N, Zhou J, Kozikowski AP, Wroblewski JT, Shamimi-Noori S, Wroblewska B, Bzdega T, Vicini S, Barton FB, Neale JH (2004). NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group mGluR. J Neurochem. 89(4):876-85
  • Hornbeck PV, Chabra I, Kornhauser JM, Skrzypek E, Zhang B (2004). PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation. Proteomics. 4(6):1551-61. PMID: 15174125
  • Rusu, L., Gambhir, A., McLaughlin, S. and Raedler, J. (2004). Fluorescence correlation spectroscopy studies of Peptide and protein binding to phospholipid vesicles. Biophys. J. 87:1044-53. PMID: 15298909
  • Gambhir, A., Hangyás-Mihályné, G., Zaitseva, I., Cafiso, D.S., Wang, J., Murray, D., Pentyala, S.N., Smith, S.O., and McLaughlin, S. (2004). Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophys. J. 86:2188-2207. PMID: 15041659
  • Wang, J., Gambhir, A., McLaughlin, S.M., and Murray, D. (2004). A Computational Model for the Electrostatic Sequestration of PI(4,5)P2 by Membrane-Adsorbed Basic Peptides. Biophys J. 86:1969-86. PMID: 15041641
  • Janardhan A, Swigut T, Hill B, Myers MP, and Skowronski J (2004). HIV-1 Nef Binds the DOCK2-ELMO1 Complex to Activate Rac and Inhibit Lymphocyte Chemotaxis. PLoS Biol. 2(1):E6. PMID: 14737186
  • LaLonde, M. and Frohman, M.A. (2004). Phospholipase D. In Encyclopedia of Biological Chemistry. (eds. Lennarz, W. and Lane, M.D.). Academic Press/ Elsevier. 3:306-313
  • Manganas L.N. and Trimmer J.S. (2004). Calnexin regulates mammalian Kv1 channel trafficking. Biochemical and Biophysical Research Communications. 322:577-84. PMID: 15325269
  • Zijlstra, A., Aimes, R.T., Zhu, D., Regazzoni, K., Kupriyanova, T., Seandel, M., Deryugina, EI., and Quigley, J.P. (2004). Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3). J. Biol Chem. 279:27633-45
  • Szema, R., Rastegar, J., and Lee, L. (2004). An artificial compound eye for stereoendoscopy.J. Med. Eng. Technol. 28:117-24. PMID: 15204617

2003

  • *Hu C, Ahmed M, Melia TJ, Sollner TH, Mayer T, Rothman JE. (2003). Fusion of cells by flipped SNAREs. Science. 300:1745-9
  • Guo, H., Seixas-Silva, J.A. Jr., Epperly, M.W., Gretton, J.E., Shin, D.M., Bar-Sagi, D., Archer, H., and Greenberger, J.S. (2003). Prevention of radiation-induced oral cavity mucositis by plasmid/liposome delivery of the human manganese superoxide dismutase (SOD2) transgene.Radiat. Res. 159:361-70. PMID: 12600239
  • Epperly, M.W., H.L. Guo, M. Jefferson, S. Nie, J. Gretton, M. Bernarding, D. Bar-Sagi, H. Archer and J.S. Greenberger. (2003). Cell Phenotype Specific Kinetics of Expression of Intratracheally Injected Manganese Superoxide Dismutase-plasmid/liposomes (MnSOD-PL) during Lung Radioprotective Gene Therapy. Gene Therapy. 10:163-171. PMID: 12571645
  • Bhatt, DH, New York State MSTP Researchers Competition, Functional Regeneration in Zebrafish 9/2003
  • Bhatt, DH and Fetcho, JR, New York State Spinal Cord Research Awards and Symposium, Functional Regeneration and In vivo imaging 2/2003
  • Bien H, Yin L and Entcheva E (2003). Cardiac cell networks on elastic microgrooved scaffolds.IEEE Eng Med Biol. 22(5):108-112. PMID: 14699943
  • Entcheva E and Bien H (2003). Tension development and nuclear eccentricity in topographically controlled cardiac syncytium. Biomedical Microdevices. 5(2): 163-168
  • Cuenca A, Cheng F, Wang H, Brayer J, Horna P, Gu L, Bien H, Borrello IM, Levitsky HI, and Sotomayor EM (2003). Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens. Cancer Res. 63:9007-15
  • *Johansson, BE and Brett, IC. (2003). Variation in divalent cation requirements of influenza A virus N2 neuraminidases. J Biochem. 134(2):345-352
  • *Brown ST, Brett I, Almenoff PL, Lesser M, Terrin M, Teirstein AS. (2003). Recovery of cell wall deficient organisms from blood does not distinguish between subjects with sarcoidosis and controls. Chest. 123(2):413-7
  • *Kilbourne ED, Smith C, Brett I, Pokorny BA, Johansson B, Cox N. The total influenza vaccine failure of 1947 revisited: major intrasubtypic antigenic change can explain failure of vaccine in a post-World War II epidemic. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10748-52. Epub 2002 Jul 22. Erratum in: Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):764. PMID:12136133
  • Makowski A, Brzostek S, Cohen RN, Hollenberg AN. (2003). Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor. Mol Endocrinol. 17(2):273-86
  • Price, K. S., Friend, D. S., Mellor, E. A., De Jesus, N., Watts, G. F., and J. A. Boyce. (2003). CC chemokine receptor 3 mobilizes to the surface of human mast cells and potentiates immunoglobulin E-dependent generation of interleukin 13. Am. J. Respir. Cell. Mol. Biol. 28:420-427
  • Newman, GC, Delucia-Deranja, E, Tudorica, A, Hospod, F.E., and Patlak, C.S. (2003). Cerebral blood volume measurements by T*2-weighted MRI and contrast infusion. Magn. Reson. Med. 50:844-55. PMID: 14523972
  • Grace, K.S., Bronson, R.A., and Ghebrehiwet, B. (2003). Ligation of the C1q Receptor,gC1qR/p33, Associates with Both the avb3 Integrin and Vitronectin and Causes Protein Phosphorylation. Fertil Steril. 80:S5
  • Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., and Malinow, R. (2003). APP Processing and Synaptic Function. Neuron. 37(6):925-37. PMID: 12670422
  • Indyk, J.A., Chen, Z.-l., Tsirka, S.E., and Strickland, S. (2003). Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury.Neuroscience. 116:359-71. PMID: 12559092
  • Chen, Z.-l., Indyk, J.A., and Strickland, S. (2003). The hippocampal laminin matrix is dynamic and critical for neuronal survival. Molecular Biology of the Cell. 14:2665-2676. PMID: 12857855
  • *Cohen, R.N., Cohen, L.E., Botero, D., Yu, C., Sagar, A., Jurkiewicz M., Radovick, S. (2003). "Enhanced Repression by HESX1 as a Cause of Hypopituitarism and Septooptic Dysplasia." J Clin Endocrinol Metab. 88(10): 4832-4839
  • Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., and Malinow, R. (2003). APP processing and synaptic function. Neuron. 37:925-37. PMID: 12670422
  • Kim, E.J., and Helfman, D. M. (2003). Characterization of the metastasis-associated protein, S100A4. Roles of calcium binding and dimerization in cellular localization and interaction with myosin. J. Biol Chem. 278:30063-30073. PMID: 12756252
  • Suzuki, T., Kwofie, M.A., and Lennarz, W.J. (2003). Ngly1, a mouse gene encoding a deglycosylating enzyme implicated in proteasomal degradation: expression, genomic organization, and chromosomal mapping. Biochem. Biophys. Res. Commun. 304:326-32
  • Mittra, E.S., A.J. Singer, D. Bluestein, and J.D. Hollander (2003). Simulated wound irrigation impact pressures. Israeli Journal of Emergency Medicine. 3:9-16
  • Pessler, F. and Hernandez, N. (2003). Flexible DNA binding of the BTB/POZ-domain protein FBI-1. J. Biol. Chem. 31:29327-35. PMID: 12750370
  • Sturla, L., Rampal, R., Haltiwanger, R.S., Fruscione, F., Etzioni, A., and Tonetti, M. (2003). Differential Terminal Fucosylation of N-linked Glycans Versus Protein O-fucosylation in Leukocyte Adhesion Deficiency Type II (CDG IIc). J. Biol. Chem. 278:26727-733. PMID: 12738772
  • Wang, J., Rogove, A.D., Tsirka A.E. and Tsirka, S.E. (2003). Protective Role of Tuftsin Fragment 1-3 in an Animal Model of Intracerebral Hemorrhage. Annals of Neurology. 54:655-664. PMID: 14595655
  • Brian P. Helmke, Amy B. Rosen, and Peter F. Davies (2003). Mapping Mechanical Strain of an Endogenous Cytoskeletal Network in Living Endothelial Cells. Biophys. J. 84:2691-2699
  • Weston C., Gordon C, Teressa G, Hod E, Ren XD, and Prives J (2003). Cooperative regulation by Rac and Rho of agrin-induced acetylcholine receptor clustering in muscle cells. J. Biol. Chem. 278(8):6450-5. PMID:12473646

2002

  • Epperly, M.W., Sikora, C.A., DeFilippi, S.J., Gretton, J.E., Bar-Sagi, D., Archer, H., Carlos, T., Guo, H., and Greenberger, J.S. (2002). Pulmonary irradiation-induced expression of VCAM-I and ICAM-I is decreased by manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) gene therapy. Biol. Blood Marrow Transplant. 8:175-87. PMID: 12014807
  • Archer, H. and D., Bar-Sagi. (2002). Ras and Rac as Activators of Reactive Oxygen Species (ROS). Methods Mol. Biol. 189:67-73. PMID: 12094595
  • Wiestner A, Cho HJ, Asch AS, Michelis MA, Zeller JA, Peerschke EI, Weksler BB, Schechter GP. (2002). Rituximab in the treatment of acquired factor VIII inhibitors. Blood. 100(9):3426-8. PMID: 12384448
  • *Brett, I., J. Werber, and E.D. Kilbourne. (2002). Rapid confirmation by RFLP of transfer to vaccine candidate reassortment viruses of the principal 'high yield' gene of influenza A viruses.J Virol Methods. 100:133-40
  • Kilbourne ED, Smith C, Brett I, Pokorny BA, Johansson B, Cox N. (2002). The total influenza vaccine failure of 1947 revisited: Major intrasubtypic antigenic change can explain failure of vaccine in a post-World War II epidemic. Proc Nat Acad Sci. 99(16):10748-10752
  • Cheng S, Brzostek S, Lee SR, Hollenberg AN, Balk SP. (2002). Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Mol Endocrinol. 16(7):1492-501
  • Bacich DJ, Ramadan E, O’Keefe DS, Bukhari N, Wegozsewska I, Ojeifo O, Olszewski R, Wrenn CC, Bzdega T, Wroblewska B, Heston WD, Neale JH. (2002). Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate. J Neurochem. 83(1):20-9
  • Chen, G., and Stenlund, A. (2002). Sequential and ordered assembly of E1 initiator complexes on the papillomavirus origin of DNA replication generates progressive structural changes related to melting. Mol. Cell Biol. 22:7712-20. PMID: 11119599
  • Tudorica, A., Li, H., Hospod, F.E., DeLucia-Deranja, E., Huang, W., Patlak, C.S., and Newman, G.C. (2002). Cerebral Blood Volume Measurements by Rapid Contrast Infusion and T2*-Weighted Echo Planar MRI. Magn. Reson. Med. 47:1145-1157. PMID: 12111961
  • Wang J., Gambhir A., Hangyás-Mihályné G., Murray D., Golebiewska U., and McLaughlin S. (2002). How Phosphatidylinositol 4,5-Bisphosphate Binds to the Basic Effector Domain of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS). J. Biol. Chem. 277(37):34401-12. PMID: 12097325
  • McLaughlin, S., Wang, J., Gambhir, A., and Murry, D. (2002). PIP2 and Proteins: Interactions, Organization and Information Flow. Annual Rev. of Biophysics Biomolecular Structure. 31:151-75. PMID: 11988466
  • Grace, K.S., Bronson, R.A., and Ghebrehiwet, B. (2002). Surface Expression of Complement Receptor gC1q-R/p33 Is Increased on the Plasma Membrane of Human Spermatozoa after Capacitation. Biol. Reprod. 66: 823-9. PMID: 11870091
  • Munch, J., Janardhan, A., Stolte, N., Stahl-Hennig, C., Ten Haaft, P., Heeney, J.L., Swigut, T., Kirchhoff, F., and Skowronski, J. (2002). T-cell receptor:CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques. J. Virol. 76:12360-4. PMID: 12414978
  • Evinger, C., Bao, J.B., Powers, A.S., Kassem, I.S., Schicatano, E.J., Henriquez, V.M., and Peshori, K.R. (2002). Dry eye, blinking, and blepharospasm. Mov. Disord. 17:S75-8. PMID: 11836761
  • Petrov AI, Khalil DN, Kazaryan RL, Savintsev IV, Sukhorukov B (2002). Structural and thermodynamic features of complexes formed by DNA and synthetic polynucleotides with dodecylamine and dodecyltrimethylammonium bromide. Bioelectrochemistry. 58(1):75-85. PMID: 12401573
  • Araya, E., Berthier, C., Kim, E., Yeung, T., Wang, X., and Helfman, D. M. (2002). Regulation of coiled-coil assembly in tropomyosins. J. Struct. Biol. 137:176-183. PMID: 12064944
  • Campomanes C.R., Carroll K.I., Manganas L.N., Hershberger M.E., Gong B., Antonucci D.E., Rhodes K.J., and Trimmer J.S. (2002). Kv?Beta Subunit Oxidoreductase Activity and Kv1 Potassium Channel Trafficking. Journal of Biological Chemistry. 277:8298-8305. PMID: 11748234
  • Rubin, C., Turner, A.S., Muller, R., Mittra, E., McLeod, K., Lin, W., and Qin, Y.X. (2002). Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention. Journal of Bone and Mineral Res. 17:349-57. PMID: 11811566
  • Rogove, A.D., Lu, W., and Tsirka S.E. (2002). Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration. Cell Death and Differentiation. 9(8):801-6. PMID: 12107823
  • Gil, O.D., Zhang, L., Chen, S., Ren, Y.Q., Pimenta, A., Zanazzi, G., Hillman, D., Levitt, P. and Salzer, J.L. (2002). Complementary expression and heterophilic interactions between IgLON family members neurotrimin and LAMP. J. Neurobiol. 51:190-204
  • Rambukkana, A., Zanazzi, G., Tapinos, N. and Salzer, J.L. (2002). Contact-dependent induction of demyelination by Mycobacterium leprae in the absence of immune cells. Science. 296:927- 931
  • Chen, S., Gil, O.D., Ren, Y.Q., Zanazzi, G., Salzer, J.L. and Hillman, D. (2002). Neurotrimin expression during cerebellar development suggests roles in axon fasciculation and synaptogenesis. J. Neurocytol. 30:927-937

2001

  • Ritter, D.A., Bhatt, D.H., and Fetcho, J.R. (2001). In vivo imaging of zebrafish reveals differences in the spinal networks for escape and swimming movements. J. Neurosci. 21:8956-65. PMID: 11698606
  • Cohen RN, Brzostek S, Kim B, Chorev M, Wondisford FE, Hollenberg AN. (2001). The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains. Mol Endocrinol. 15(7):1049-61
  • Chen, G., and Stenlund, A. (2001). The E1 initiator recognizes multiple overlapping sites in the papillomavirus origin of DNA replication. J. Virol. 75:292-302
  • Ho, L., Xiang, Z., Mukherjee, P., Zhang, W., De Jesus, N., Mirjany, M., Yemul, S., and G. M. Pasinetti. (2001). Gene expression profiling of the tau mutant (P301L) transgenic mouse brain.Neurosci. Lett. 310:1-4
  • DiMartino, S.J., Shah, A.B., Trujillo, G., and Kew, R.R. (2001). Elastase controls the binding of the vitamin D-binding protein (Gc-globulin) to neutrophils: a potential role in the regulation of C5a co-chemotactic activity. J. Immunol. 166:2688-94. PMDI: 11160333
  • Singh, N., Talalayeva, Y., Tsiper M., Romanov, V., Dranovsky, A., Colflesh, D., Rudamen, G., Vitek, M.P., Shen, J., Yang, X.D., Goldgaber, D., and Schwarzman, A.L. (2001). The role of Alzheimer's disease-related presenilin 1 in intercellular adhesion. Exp. Cell Res. 263:1-13. PMDI: 11161700
  • Dranovsky, A., Vincent, I., Gregori L., Schwarzman, A.L., Enghild, J., Strittmatter, W., Davies, P., and Goldgaber, D. (2001). Cdc2 phosphorylated nucleolin demarcates mitotic changes and Alzheimer’s disease pathology. Neurobiol of Aging. 22(4):517-28. PMDI: 11445251
  • Suzuki, T., Park, H., Kwofie, M.A., and Lennarz, W.J. (2001). Rad23 provides a link between the Png1 deglycosylating nzyme and the 26 S proteasome in yeast. J. Biol. Chem. 276:21601-7
  • Robert L. Levine, Holly Miller, Arthur Grollman, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, and Masaaki Moriya (2001). Translesion DNA synthesis catalyzed by human pol h and pol k across 1,N6-ethenodeoxyadenosine. Journal of Biological Chemistry. 276(22):18717-21. PMDI: 11376002
  • Manganas L.N., Wang Q., Scannevin R.H., Antonucci D.E., Rhodes K.J., and Trimmer J.S. (2001). Identification of a Trafficking Determinant Localized to the Kv1 Potassium Channel Pore. Proceedings of the National Academy of Science. 98(24):14055. PMDI: 11698661
  • Manganas L.N., Akhtar S., Antonucci D.E., Campomanes C.R., Oliver Dolly J. and Trimmer J.S. (2001). Episodic Ataxia Type-1 Mutations in the Kv1.1 Potassium Channel Display Distinct Folding and Intracellular Trafficking Properties. Journal of Biological Chemistry. 276(52):49427-34. PMDI: 11679591
  • Seandel, M., Noack-Kunnmann, K., Zhu, D., Aimes, R.T., and Quigley. J.P. (2001). Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen.Blood. 97:2323-32
  • Lustig M., Zanazzi G., Sakurai T., Blanco C., Levinson S.R., Lambert S., Grumet M., and Salzer J.L. (2001). Nr-CAM and neurofascin interactions regulate ankyrin G and sodium channel clustering at the node of Ranvier. Curr. Biol. 11:1864-1869. *Equal contribution
  • Melendez-Vasquez, C., Rios, J.C., Zanazzi, G., Bretscher, A., Lambert, S. and Salzer, J.L. (2001). Nodes of Ranvier form in association with ERM-positive Schwann cell microvilli. Proc. Natl. Acad. Sci. 98:1235-1240
  • Zanazzi, G., Einheber, S., Westreich, R., Hannocks, M.-J., Bedell-Hogan, D., Marchionni, M.A. and Salzer, J.L. (2001). Glial growth factor/neuregulin inhibits myelination and induces demyelination. J. Cell Biol. 152:1289-1299

2000

  • W.S. Asch and N. Schechter. (2000). Plasticin, a Type III Neuronal Intermediate Filament Protein, Assembles as an Obligate Heteropolymer: Implications for Axonal Flexibility. J. Neurochem. 75:1475-1486
  • McCaughran, J.A. Jr., Bell, J. III, and Hitzemann, R.J. (2000). Fear-potentiated startle response in mice: genetic analysis of the C57BL/6J and DBA/2J intercross. Pharmacol. Biochem. Behav. 65(2):301-12. PMDI. 10672983
  • Enemark, E.J., Chen, G., Vaughn, D.E., Stenlund, A., and Joshua-Tor, L. (2000). Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus.Mol. Cell. 6:149-58. PMDI: 10949036
  • Gillitzer, E., Chen, G., and Stenlund, A. (2000). Separate domains in E1 and E2 proteins serve architectural and productive roles for cooperative DNA binding. EMBO J. 19:3069-79. PMDI: 10856250Chen, G., and Stenlund, A. (2000). Two patches of amino acids on the E2 DNA binding domain define the surface for interaction with E1. J. Virol. 74:1506-12. PMDI: 10627562
  • Ochi, H., De Jesus, N. H., Hsieh, F. H., Austen, K. F., and J. A. Boyce. (2000). IL-4 and -5 prime human mast cells for different profiles of IgE-dependent cytokine production. Proc. Natl. Acad. Sci. USA. 97:10509-10513
  • Carl, S., Iafrate, A.J., Lang, S.M., Stolte, N., Stahl-Hennig, C., Matz-Rensing, K., Fuchs, D., Skowronski, J., and Kirchhoff, F. (2000). Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques. J. Virol. 74(9):4155-64. PMDI: 10756028
  • Iafrate, A.J., Carl, S., Bronson, S., Stahl-Hennig, C., Swigut, T., Skowronski, J., and Kirchhoff, F. (2000). Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo. J. Virol. 74:9836-44. Erratum in: J. Virol . 74:12002. PMDI: 11024110
  • Swigut, T., Iafrate, A.J., Muench, J., Kirchhoff, F., and Skowronski, J. (2000). Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression. J. Virol. 74(12):5691-701. PMDI: 10823877
  • Carl, S., Daniels, R., Iafrate, A.J., Easterbrook, P., Greenough, T.C., Skowronski, J., and Kirchhoff, F. (2000). Partial "repair" of defective NEF genes in a long-term nonprogressor with human immunodeficiency virus type 1 infection. J. Infect Dis. 181(1):132-40. PMDI: 10608759
  • Robert L. Levine, In-Young Yang, Munfarah Hossain, Gagan A. Pandya, Arthur P. Grollman, and Masaaki Moriya (2000). Mutagenesis induced by a Single 1,N6-Ethenodeoxyadenosine Adduct in Human Cells. Cancer Research. 60(15):4098-104. PMDI: 10945616
  • Tiffany A.F., Manganas L.N., Kim E., Sheng M., and Trimmer J.S. (2000). PSD-95 and SAP-97 Exhibit Distinct Mechanisms for Regulating K+ Channel Surface Expression and Clustering.Journal of Cell Biology. 148(1):147-58. PMDI: 10629225
  • Manganas L.N. and Trimmer J.S. (2000). Subunit Composition Determines Kv1 Potassium Channel Surface Expression. Journal of Biological Chemistry. 275(38):29685. PMDI: 10896669
  • Melchor JP, McVoy L, and Van Nostrand WE (2000). Charge alterations of E22 enhance the pathogenic properties of amyloid beta-protein. J. Neurochem. 74:2209-2212
  • Weston, C.A., Anova, L., Rialas,C., Prives, J.M., and Weeks, B.S. (2000). Laminin-1 activates Cdc42 in the mechanism of laminin-1-mediated neurite outgrowth. Exp. Cell Res. 260:374-8
  • Weston, C., Yee, B., Hod, E., and Prives, J. (2000). Agrin-induced acetylcholine receptor clustering is mediated by the small Rho guanine nucleotide exchange factors Rac and Cdc42.J. Cell Biol. 150:205-212
  • Rialas, C.M., Nomizu, M., Patterson, M., Kleinman, H.K., Weston, C.A., and Weeks, B.S. (2000). Nitric oxide mediates laminin-induced neurite outgrowth in PC12 cells. Exp. Cell Res. 260:374-378
  • Ng, V.*, Zanazzi, G.*, Timpl, R., Talts, I.F., Salzer, J.L., Brennan, P.J. and Rambukkana, A. (2000). Role of the cell wall phenolic glycolipid-1 in the peripheral nerve predilection of Mycobacterium leprae. Cell. 103:511-524. *Equal contribution
  • Tikoo, R., Zanazzi, G., Shiffman, D., Salzer, J. and Chao, M.V. (2000). Cell cycle control of Schwann cell proliferation: role of cyclin-dependent kinase-2. J. Neurosci. 20:4627-4634

1999

  • *Hunt JA, Ahmed M, Fierke CA. (1999). Metal binding specificity in carbonic anhydrase is influenced by conserved hydrophobic core residues. Biochemistry. 38:9054-62
  • Leake, D , W.S. Asch, Canger, A.K., and Schechter, N. (1999). Gefiltin expression in zebrafish embryos: sequential expression of two neurofilament proteins in retinal ganglion cells. Differentiation. 65:181-189
  • McCaughran, J. Jr., Bell, J., and Hitzemann, R. (1999). On the relationships of high-frequency hearing loss and cochlear pathology to the acoustic startle response (ASR) and prepulse inhibition of the ASR in the BXD recombinant inbred series. Behav Genet. 29(1):21-30. PMDI: 10371755
  • Sotomayor EM, Borrello I, Tubb E, Rattis FM, Bien H, Lu Z, Fein S, Schoenberger S, and Levitsky HI (1999). Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nature Medicine. 5:780-7
  • DiMartino, S.J., and Kew, R.R. (1999). Initial characterization of the vitamin D binding protein (Gc-globulin) binding site on the neutrophil plasma membrane: evidence for a chondroitin sulfate proteoglycan. J. Immunol. 163:2135-42. PMDI: 10438954
  • Faris S., Wilson D., Barrett H., Dougherty D., Gindi G., Hsiao I.T. (1999). Using a digital anatomical phantom to optimize an imaging system. In Proc. SPIE Medical Imaging. vol. 3659
  • Schwarzman, A. L., Singh, N., Tsiper, M., Gregori, L., Dranovsky, A., Vitek M. P., Glabe, C.G., St. George-Hyslop, P., and Goldgaber, D. (1999). Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix. Proc. Nat. Acad. Sci. 96(14):7932-7. PMDI: 10393925
  • Kazantsev, A., Preisinger, E., Dranovsky, A., Goldgaber, D., and Housman, D. (1999). Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proc. Nat. Acad. Sci. 96(20):11404-9. PMDI: 10500189
  • Murray D., Arbuzova A., Mihalyne G., Gambhir A., Ben-Tal N., Honig B., and McLaughlin S. (1999). Electrostatic Properties of Membranes Containing Acidic Lipids and Adsorbed Basic Peptides: Theory and Experiment. Biophys. J. 77(6):3176. PMDI: 10585939
  • Skowronski, J., Greenberg, M.E., Lock, M., Mariani, R., Salghetti, S., Swigut, T., and Iafrate, A.J. (1999). HIV and SIV Nef modulate signal transduction and protein sorting in T cells. Cold Spring Harb. Symp. Quant. Biol. 64:453-63. ( Review). PMDI: 11232322
  • Lock, M., Greenberg, M.E., Iafrate, A.J., Swigut, T., Muench , J., Kirchhoff, F., Shohdy, N., and Skowronski, J. (1999). Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. EMBO J. 18(10):2722-33. PMDI: 10329619
  • Carl, S., Iafrate, A.J., Lang, S.M., Stahl-Hennig, C., Kuhn, E.M., Fuchs, D., Matz-Rensign, K., Ten Haaft, P., Heeney, J.L., Skowronski, J., and Kirchhoff, F. (1999). The acidic region and conserved putative protein kinase C phosphorylation site in Nef are important for SIV replication in rhesus macaques. Virology. 257(1):138-55. PMDI: 10208928
  • Carl, S., Iafrate, A.J., Skowronski, J., Stahl-Hennig, C., and Kirchhoff, F. (1999). Effect of the attenuating deletion and of sequence alterations evolving in vivo on simian immunodeficiency virus C8-Nef function. J. Virol. 73(4):2790-7. PMDI: 10074126
  • Indyk, J.A., Chen, Z.-L., and Strickland, S. (1999). Proteases and degradation of extracellular matrix in neurodegeneration. Fibrinolysis & Proteolysis. 13:64-71
  • Chen, Z.-l., Indyk, J.A., Bugge, T.H., Kombrinck, K.W., Degen, J.L, and Strickland, S. (1999). Neuronal death and blood-brain barrier breakdown after excitotoxic injury are independent processes. J. Neuroscience. 19:9813-9820. PMDI: 10559390
  • Liu, M., Lee, B.H., and Mathews, M.B. (1999). Involvement of RFX1 protein in the regulation of the human proliferating cell nuclear antigen promoter. J. Biol. Chem. 274:15433-39
  • Rogove, A.D., Siao C-J, Keyt, B., Strickland, S. and Tsirka, S. E. (1999). Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system. Journal of Cell Science. 112:4007-4016. PMDI: 10547361
  • Venkatesan, C., and Kritzer, M.F. (1999). Perinatal gonadectomy affects corticocortical connections in motor but not visual cortex in adult male rats. J. Comp. Neurol. 415:240-65. PMDI: 10545163
  • Ching, W., Zanazzi, G., Levinson, S.R. and Salzer, J.L. (1999). Clustering of neuronal sodium channels requires contact with myelinating Schwann cells. J. Neurocytol. 28:295-301

1998

  • Alexander, D.S., Sipley, J.D., and Quigley, J.P. (1998). Autoactivation of avian urokinase-type plasminogen activator (uPA). A novel mode of initiation of the uPA/plasmin cascade. J. Biol. Chem. 273:7457-61. PMDI: 9516444
  • W.S., Asch, D., Leake, A.K., Canger, M., Passini, F., Argenton, and N., Schechter. (1998). Cloning of the Zebrafish Neurofilament Proteins Plasticin and Gefiltin: Increased mRNA Expression in Retinal Ganglion Cells After Optic Nerve Crush. J. Neurochem. 71:20-32
  • M.A., Passini, L. Kurtzman, A. K., Canger, W. S., Asch, G. A., Wray, P. A., Raymond, and N. Schechter. (1998). Cloning of Zebrafish vsx1: Expression of a paired-Like homeobox Gene During CNS Development. Dev. Genetics. 23:128-141
  • A.K. Canger, M. Passini, W. S. Asch, D. Leake, B. T. Zafonte, E. Glasgow, and N. Schechter. (1998). Restricted Expression of the Neurofilament Protein Plasticin During Zebrafish Development. J. Comp. Neurol. 399:561-572
  • Chen, G., and Stenlund, A. (1998). Characterization of the DNA-binding domain of the bovine papillomavirus replication initiator E1. J. Virol. 72:2567-76. PMDI: 9525573
  • Dougherty D.A., Hsiao I.T., Wang W., and Gindi G.R. (1998). Computerized Biological Brain Phantom for Evaluation of PET and SPECT Reconstruction. IEEE Transactions in Nuclear Sci. 45:1238-43
  • Greenberg, M.E., Iafrate, A.J., Skowronski, J. (1998). The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 17(10):2777-89. PMDI: 9582271
  • Lee, B.H., Liu M, Mathews, M.B. (1998). Regulation of the human proliferating cell nuclear antigen promoter by the adenovirus E1A-associated protein. J. Virol. 72:1138-45
  • Gening, L., Takeshita, M., Levine, R.L., Peden, K.W., and Grollman, A.P. (1998). Extrachromosomal unequal homologous recombination and gene conversion in simian kidney cells: effects of UV damage. Mutation Research. 407(1):11-24. PMDI: 9539977
  • Pessler, F. and Hernandez, N. (1998). The HIV type 1 inducer of short transcripts activates the synthesis of DRB resistant short transcripts in vitro. J. Biol. Chem. 273:5375-84. PMDI: 9478998
  • Rogove, A.D. and Tsirka, S.E. (1998). Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus. Current Biology. 8(1):19-25. PMDI: 9427623
  • Galbiati, F., Volonte, D., Gil, O., Zanazzi, G., Salzer, J.L., Sargiacomo, M., Scherer, P.E., Engelman, J.A., Schlegel, A., Parenti, M., Okamoto, T. and Lisanti, M.P. (1998). Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury. Proc. Natl. Acad. Sci. 95:10257-10262
  • Rambukkana, A., Yamada, H., Zanazzi, G., Mathus, T., Salzer, J.L., Yurchenco, P.D., Campbell, K.P. and Fischetti, V.A. (1998). Role of alpha-dystroglycan as a Schwann cell receptor for Mycobacterium leprae. Science. 282:2076-2079
  • Gil, O.D., Zanazzi, G., Struyk, A. and Salzer, J.L. (1998). Neurotrimin mediates bifunctional effects on neurite outgrowth via homophilic and heterophilic interactions. J. Neurosci.18:9312- 9325

1997

  • Sipley, J.D., Alexander D.S., Testa J.E., and Quigley, J.P. (1997). Introduction of an RRHR motif into chicken urokinase-type plasminogen activator (ch-uPA) confers sensitivity to plasminogen activator inhibitor (PAI)-1 and PAI-2 and allows ch-uPA-mediated extracellular matrix degradation to be controlled by PAI-1. Proc. Natl. Acad. Sci. USA. 94:2933-8. PMDI: 9096324
  • Kew, R.R., Peng, T., DiMartino, S.J., Madhavan, D., Weinman, S.J., Cheng, D., and Prossnitz, E.R. (1997). Undifferentiated U937 cells transfected with chemoattractant receptors: a model system to investigate chemotactic mechanisms and receptor structure/function relationships. J. Leukoc. Biol. 61:329-37. PMDI: 9060456
  • Gindi G., Dougherty D., Hsiao I., and Rangarajan A. (1997). Autoradiographic-based phantoms for emission tomography. In Proc. SPIE Medical Imaging. 3034:403-414.
  • Lang, S.M., Iafrate, A.J., Stahl-Hennig, C., Kuhn, E.M., Nisslein, T., Kaup, F.J., Haupt, M., Hunsmann, G., Skowronski, J., and Kirchhoff, F. (1997). Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Nat. Med. 3(8):860-5. PMDI: 9256276
  • Iafrate, A.J., Bronson, S., and Skowronski, J. (1997). Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J. 16(4):673-84. PMDI: 9049297
  • Lee, B.H., and Mathews, M.B. (1997). Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein. Proc. Natl. Acad. Sci. USA. 94:4481-6
  • Wreden, C., Verrotti, A.C., Schisa, J.A., Lieberfarb, M.E., and Strickland, S. (1997). Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA. Development. 124:3015-23. PMDI: 9247343
  • Pessler, F., Pendergrast P.S., and Hernandez, N. (1997). Purification and characterization of FBI-1, a cellular factor that binds to the HIV type 1 inducer of short transcripts. Mol. Cell. Biol. 17:3786-3798. PMDI: 9199312
  • Tsirka, S.E., Rogove, A.D., Bugge, T., Degen, J. and Strickland, S. (1997). An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J. Neuroscience. 17(2):543-52. PMDI: 8987777
  • Einheber, S., Zanazzi, G., Ching, W., Scherer, S., Milner, T.A., Peles, E. and Salzer, J.L. (1997). The axonal membrane protein Caspr/neurexin IV is a component of the septate-like paranodal junctions that assemble during myelination. J. Cell Biol. 139:1495-1506

1996

  • Alexander, D.S., Aimes, R.T., and Quigley, J.P. (1996). What structure and function of avian plasminogen activator and matrix metalloproteinase-2 reveal about their counterpart mammalian enzymes, their regulation and their role in tumor invasion. Enzyme Protein. 49(1-3):38-58. PMDI: 8796996. (Review)
  • Bhatt, DH, Green, BA , (1996). The Molecular Biology of Regeneration in the CNS. Concepts in Neurosurgery: The Molecular Basis of Neurological Disease. 80:111-169
  • Dranovsky, A., Oxberry, W., Lyubsky, S., and Goldgaber, D. (1996). APP is associated with mitotic centrosomes and a distinct cytoplasmic network which colocalizes with depolymerized tubulin. Neurobiology of Aging. 17:S196-S196
  • Wade, P.R., Chen, J., Kassem, I.S., Blakely, R.D., and Gershon, M.D. (1996). Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. J. Neurosci. 16:2352-2364
  • Lieberfarb, M.E., Chu, T., Wreden, C., Theurkauf, W., Gergen, J.P., and Strickland, S. (1996). Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development. Development. 122:579-88. PMDI: 8625809
  • Bekele-Arcuri Z, Matos MF, Manganas L, Strassle BW, Monaghan MM, Rhodes KJ, Trimmer JS. (1996). Generation and characterization of subtype-specific monoclonal antibodies to K+ channel alpha- and beta-subunit polypeptides. Neuropharmacology. 35(7):851-65. PMID: 8938716
  • Strickland, S., Gualandris, A., Rogove, A.D. and Tsirka, S. E. (1996). Extracellular proteases in neuronal function and degeneration. CSH Symposia on Quantitative Biology. 61:739-745. PMDI: 9246499
  • Tsirka, S.E., Rogove, A.D. and Strickland, S. (1996). tPA and neuronal death. Nature. 384(6605):123-4. PMDI: 8906786.

1995

  • Dranovsky, A., Goldfarb, L., Gajdusek, D.C., and Goldgaber, D. (1995). Apolipoprotein E epsilon 4 allele does not correlate with amyloid plaques in transmissible spongiform encephalopathies. Amyloid: Int. J. Exp. Clin. Invest. 2:36-38
  • Labrie, C., Lee, B.H., and Mathews, M.B. (1995). Transcription factors RFX1/EF-C and ATF-1 interact with the adenovirus E1A-responsive element of the human proliferating cell nuclear antigen promoter. Nuc. Acids Res. 23:3732-41

1994

  • Stefansson, S., Aimes, R.T., Seward, N.B., Alexander, D.S., and Quigley, J.P. (1994). Native TIMP-free 70 kDa progelatinase (MMP-2) secreted at elevated levels by RSV transformed fibroblasts. J. Cell. Physiol. 161:419-28. PMDI: 7962125
  • Salles, F.J., Lieberfarb, M.E., Wreden, C., Gergen, J.P., and Strickland, S. (1994). Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. Science. 266:1996-9. PMDI: 7801127
  • Desser, T.S., Rubin, D.L., Muller, H.H., Qing, F., Khodor, S., Zanazzi, G., Young, S.W., Ladd, D.L., Wellons, J.A., Kellar, K.E., Toner, J.L. and Snow, R.A. (1994). Dynamics of tumor imaging with Gd-DTPA-polyethylene glycol polymers: dependence on molecular weight. J. Mag. Res. Imag. 4:467-472
  • Young, S.W., Sidhu, M.K., Qing, F., Muller, H.H., Neuder, M., Zanazzi, G., Mody, T.D., Hemmi, G., Dow, W., Mutch, J.D., Sessler, J.L. and Miller R.A. (1994). Preclinical evaluation of gadolinium (III) texaphyrin complex: a new paramagnetic contrast agent for magnetic resonance imaging. Invest. Radiol. 29:330-338

1991

  • Whitbread, J.A., Sims, M., and Katz, E.R. (1991). Evidence for the presence of a growth factor in Dictyostelium discoideum. Dev Genet. 12:78-81. PMDI: 2049882