The Stony Brook Research Histology Core Lab (RHCL) provides clinical and basic science investigators with access to a wide range of histological procedures. The facility is managed by the Department of Pathology and offers gross processing of research tissue and cellular specimens, including fixation, paraffin embedding, sectioning and staining. Both routine hematoxylin and eosin (H&E) and advanced immunohistochemical (IHC) staining methods are offered. The Core staff and scientific director are available to assist in the development of research protocols that depend on the processing of tissue or other cellular specimens. The core is directed by Kenneth R. Shroyer, MD, PhD.
Dr. Kenneth Shroyer is a board certified surgical pathologist and cytopathologist and has been engaged in the development of advanced methods in immunohistochemistry, in situ hybridization, and the molecular analysis of tissues for more than 30 years. Additionally, he is an expert in tissue biobanking, microdissection, and in the use of tissue microarrays.
The laboratory is equipped with an embedding station, microtomes, and automated immunostainers. Additional specialized stains may be available upon request. Additional advanced services, including preparation of research tissue microarrays, laser capture microdissection, and other methods to support tissue-based research may be arranged following consultation with the Core Lab Director. Please contact the Core Lab in advance of submitting specimens to discuss methods for sample collection and tissue fixation.
*Immunohistochemistry/Immunofluorescence (IHC/IF) initial workup required for antibodies that are not already on line in the lab and for any antibodies that have not been previously optimized for immunohistochemical staining on FFPE sections.
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